Efficacy and Safety of Finerenone Across the Ejection Fraction Spectrum in Heart Failure With Mildly Reduced or Preserved Ejection Fraction: A Prespecified Analysis of the FINEARTS-HF Trial

The effects of treatments for heart failure (HF) may vary among patients according to left ventricular ejection fraction (LVEF). In FINEARTS-HF (Finerenone Trial to Investigate Efficacy and Safety Superior to Placebo in Patients With Heart Failure), the nonsteroidal mineralocorticoid receptor antago...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 2025-01, Vol.151 (1), p.45-58
Hauptverfasser:	Docherty, Kieran F, Henderson, Alasdair D, Jhund, Pardeep S, Claggett, Brian L, Desai, Akshay S, Mueller, Katharina, Viswanathan, Prabhakar, Scalise, Andrea, Lam, Carolyn S P, Senni, Michele, Shah, Sanjiv J, Voors, Adriaan A, Zannad, Faiez, Pitt, Bertram, Vaduganathan, Muthiah, Solomon, Scott D, McMurray, John J V
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Double-Blind Method Female Heart Failure - drug therapy Heart Failure - mortality Heart Failure - physiopathology Humans Life Sciences Male Middle Aged Mineralocorticoid Receptor Antagonists - adverse effects Mineralocorticoid Receptor Antagonists - therapeutic use Naphthyridines - adverse effects Naphthyridines - therapeutic use Original s Stroke Volume - drug effects Treatment Outcome Ventricular Function, Left - drug effects
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