Association of CSF α‐synuclein seed amplification assay positivity with disease progression and cognitive decline: A longitudinal Alzheimer's Disease Neuroimaging Initiative study

INTRODUCTION Cerebrospinal fluid (CSF) α‐synuclein (α‐syn) seed amplification assay (SAA) is a sensitive and specific tool for detecting Lewy body co‐pathology in Alzheimer's disease. METHODS A total of 1637 cross‐sectional and 407 longitudinal CSF samples from the Alzheimer's Disease Neur...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Alzheimer's & dementia 2024-12, Vol.20 (12), p.8444-8460
Hauptverfasser:	Tosun, Duygu, Hausle, Zachary, Thropp, Pamela, Concha‐Marambio, Luis, Lamoureux, Jennifer, Lebovitz, Russ, Shaw, Leslie M., Singleton, Andrew B., Weiner, Michael W., Blauwendraat, Cornelis
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over alpha-Synuclein - cerebrospinal fluid Alzheimer Disease - cerebrospinal fluid Alzheimer Disease - genetics Alzheimer Disease - pathology Alzheimer's disease Amyloid beta-Peptides - cerebrospinal fluid Biomarkers - cerebrospinal fluid cognitive decline Cognitive Dysfunction - cerebrospinal fluid Cognitive Dysfunction - genetics co‐pathology Cross-Sectional Studies Disease Progression Female Humans Lewy body Longitudinal Studies Male Middle Aged Neuroimaging Peptide Fragments - cerebrospinal fluid seed amplification assay tau Proteins - cerebrospinal fluid
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!