Sea conch (Rapana venosa) peptide hydrolysate regulates NF‐κB pathway and restores intestinal immune homeostasis in DSS‐induced colitis mice

Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the gastrointestinal tract. Sea conch peptide hydrolysate (CPH) was produced by enzymatic digestion of fresh conch meat with trypsin enzyme. To analyze the molecular composition, functional groups, and structural morphology of t...

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Veröffentlicht in:	Food Science & Nutrition 2024-12, Vol.12 (12), p.10070-10086
Hauptverfasser:	Ullah, Hidayat, Alioui, Yamina, Ali, Muhsin, Ali, Sharafat, Farooqui, Nabeel Ahmed, Siddiqui, Nimra Z., Alsholi, Duaa M., Ilyas, Muhammad, Rahman, Mujeeb U., Xin, Yi, Wang, Liang
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Apoptosis Body weight Cell death Chemical composition Chromatography Colitis Colon Cytokines Damage prevention Deoxyribonucleic acid Dextran Dextran sulfate Dextrans Dietary supplements Digestive system DNA DNA damage Drug development Drug dosages Enzymes Food intake Fourier transforms FTIR Functional groups Gastrointestinal system Gastrointestinal tract Gene expression Health aspects Homeostasis Hydrolysates Immune system Immunity (Disease) Immunomodulation Immunomodulators Immunoregulation Inflammatory bowel disease Inflammatory bowel diseases Infrared analysis Infrared spectroscopy intestinal immune homeostasis Intestine Liquid chromatography Mass spectrometry Mass spectroscopy Medical research Medical treatment Molecular weight Original Peptides peptides hydrolysate Proteins R&D Research & development RNA Scanning electron microscopy scanning electronic microscopy Seafood Sulfates Trypsin Tumor necrosis factor-TNF Water intake Water intakes
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