Multipartite Fluorogenic Sensors for Monitoring Tyrosine Phosphatase Activity

Fluorogenic substrates are essential tools for studying the activity of many enzymes including the protein tyrosine phosphatases (PTPs). Here, we have taken the first step toward the development of genetically encodable sensors for PTP activity using fluorescent and fluorogen‐activating proteins. Th...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Chembiochem : a European journal of chemical biology 2024-12, Vol.25 (24), p.e202400607-n/a
Hauptverfasser:	Hansen, Daniel T., Tu, Julian, Bouck, Alison W., Mathis, Cheryl L., Barrios, Amy M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biosensing Techniques - methods Dephosphorylation Dyes Fluorescence Fluorescence assay Fluorescent Dyes - chemistry Fluorescent protein Fluorophore Humans Peptides Phosphatase Phosphorylation Protein Tyrosine Phosphatase, Non-Receptor Type 1 - antagonists & inhibitors Protein Tyrosine Phosphatase, Non-Receptor Type 1 - metabolism Protein Tyrosine Phosphatases - analysis Protein Tyrosine Phosphatases - metabolism Protein-tyrosine-phosphatase Proteins Rhodanine - analogs & derivatives Rhodanine - chemistry Rhodanine - metabolism Sensors Tyrosine
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!