Analytical Methods to Evaluate RNA Circularization Efficiency

ABSTRACT Circular RNAs (circRNAs) have emerged as pivotal players in RNA therapeutics. Unlike linear counterparts, circRNAs possess a closed‐loop structure, conferring them with enhanced stability and resistance to degradation. Ribozyme‐based strategy stands out as the predominant method for synthet...

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Veröffentlicht in:	Electrophoresis 2024-11, Vol.45 (21-22), p.2005-2011
Hauptverfasser:	Sun, Yali, Khimani, Anis H., Tong, Yanhong, Lu, Zhi‐xiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Catalytic activity circular RNA Efficiency Humans linear RNA microfluidic capillary electrophoresis Nucleic Acids RNA - analysis RNA - chemistry RNA - genetics RNA, Catalytic - chemistry RNA, Circular - analysis RNA, Circular - genetics vector engineering
Online-Zugang:	Volltext
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