Pneumococcal extracellular vesicles mediate horizontal gene transfer via the transformation machinery

Bacterial cells secrete extracellular vesicles (EVs), the function of which is a matter of intense investigation. Here, we show that the EVs secreted by the human pathogen (pneumococcus) are associated with bacterial DNA on their surface and can deliver this DNA to the transformation machinery of co...

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Veröffentlicht in:	mSphere 2024-11, Vol.9 (12), p.e0072724
Hauptverfasser:	Werner Lass, Sarah, Smith, Bailey E, Camphire, Shaw, Eutsey, Rory A, Prentice, Jojo A, Yerneni, Saigopalakrishna S, Arun, Ashni, Bridges, Andrew A, Rosch, Jason W, Conway, James F, Campbell, Phil, Hiller, N Luisa
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteriology DNA, Bacterial - genetics Drug Resistance, Bacterial - genetics Extracellular Vesicles - genetics Extracellular Vesicles - metabolism Gene Transfer, Horizontal Humans Research Article Streptococcus pneumoniae - genetics Transformation, Bacterial
Online-Zugang:	Volltext
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