Plasmablastic Lymphoma Manifesting As Pleural Thickening and Effusion: A Case Report

Plasmablastic Lymphoma Manifesting As Pleural Thickening and Effusion: A Case Report

Plasmablastic lymphoma (PbL) is a subtype of diffuse large B-cell lymphoma, primarily linked to human immunodeficiency virus (HIV) infection. This case report presents a 34-year-old HIV-positive patient who exhibited unusual signs of pleural thickening and effusion. Initial evaluations, including im...

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Veröffentlicht in:Curēus (Palo Alto, CA) CA), 2024-11, Vol.16 (11), p.e73961
Hauptverfasser: Elsayed, Mohammed, Ali, Abdelrahman, Andrijevskiene, Giedre
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Hematology
Oncology
Radiology
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description Plasmablastic lymphoma (PbL) is a subtype of diffuse large B-cell lymphoma, primarily linked to human immunodeficiency virus (HIV) infection. This case report presents a 34-year-old HIV-positive patient who exhibited unusual signs of pleural thickening and effusion. Initial evaluations, including imaging and pleural fluid analysis, suggested thoracic empyema. However, histopathological examination ultimately revealed a diagnosis of PbL. Cyclophosphamide, doxorubicin, vincristine, and prednisolone (CHOP) chemotherapy were initiated, but the patient passed away within a few months. This case highlights the complexity of diagnosing PBL and its poor prognosis, particularly in immunocompromised individuals, stressing the importance of early detection and intervention.
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Radiology
title Plasmablastic Lymphoma Manifesting As Pleural Thickening and Effusion: A Case Report
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