In vitro model of retinoblastoma derived tumor and stromal cells for tumor microenvironment (TME) studies

Retinoblastoma (RB) is an intraocular tumor arising from retinal cone progenitor cells affecting young children. In the last couple of years, RB treatment evolved towards eye preserving therapies. Therefore, investigating intratumoral differences and the RB tumor microenvironment (TME), regulating t...

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Veröffentlicht in:	Cell death & disease 2024-12, Vol.15 (12), p.905-12, Article 905
Hauptverfasser:	Alefeld, Emily, Haase, André, Van Meenen, Dario, Budeus, Bettina, Dräger, Oliver, Miroschnikov, Natalia, Ting, Saskia, Kanber, Deniz, Biewald, Eva, Bechrakis, Nikolaos, Dünker, Nicole, Busch, Maike Anna
Format:	Artikel
Sprache:	eng
Schlagworte:	13/106 13/109 13/2 13/51 14/63 38/39 38/77 38/91 631/378/1689/1690 631/67/327 631/80/304 692/308/2778 692/699/67/1484 Animals Antibodies Biochemistry Biomedical and Life Sciences Cell Biology Cell Culture Cell differentiation Cell Line, Tumor Cell Proliferation Chick Embryo Chorioallantoic membrane Chorioallantoic Membrane - metabolism Gene expression Gene Expression Regulation, Neoplastic Humans Immunofluorescence Immunology Life Sciences Macrophages Malignancy Metastases Phenotypes Progenitor cells Proteomes Retinal Neoplasms - genetics Retinal Neoplasms - metabolism Retinal Neoplasms - pathology Retinoblastoma Retinoblastoma - genetics Retinoblastoma - metabolism Retinoblastoma - pathology Serum-free medium Stromal cells Stromal Cells - metabolism Stromal Cells - pathology Trefoil factor Tumor cell lines Tumor cells Tumor Microenvironment Tumorigenesis
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