A Pooled Population Pharmacokinetic Study of Oral and Intravenous Administration of Clavulanic Acid in Neonates and Infants: Targeting Effective Beta‐Lactamase Inhibition

Data published on the oral clavulanic acid pharmacokinetics in the pediatric population is lacking. This research aimed to describe clavulanic acid disposition following oral and intravenous administration and to provide insights into clavulanic acid exposure based on threshold concentrations for (p...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Clinical pharmacology and therapeutics 2025-01, Vol.117 (1), p.193-202
Hauptverfasser:	Schouwenburg, Stef, Keij, Fleur M., Tramper‐Stranders, Gerdien A., Kornelisse, René F., Reiss, Irwin K. M., De Cock, Pieter A. J. G., Dhont, Evelyn, Watt, Kevin M., Muller, Anouk E., Flint, Robert B., Koch, Birgit C. P., Allegaert, Karel, Preijers, Tim
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Intravenous Administration, Oral Amoxicillin-Potassium Clavulanate Combination - administration & dosage Amoxicillin-Potassium Clavulanate Combination - pharmacokinetics Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - pharmacokinetics beta-Lactamase Inhibitors - administration & dosage beta-Lactamase Inhibitors - pharmacokinetics Biological Availability Clavulanic Acid - administration & dosage Clavulanic Acid - pharmacokinetics Female Humans Infant Infant, Newborn Male Models, Biological
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!