Expression patterns of H3K27me3 for differentiation of breast fibroadenomas and phyllodes tumors

Phyllodes tumors (PTs) are rare breast tumors showing overlapping features with fibroadenomas (FAs). Diagnosis on small biopsies is challenging. New diagnostic markers are needed. Here we evaluated immunohistochemical staining of histone 3 trimethyl-lysine-27 (H3K27me3) as a diagnostic and prognosti...

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Veröffentlicht in:	APMIS : acta pathologica, microbiologica et immunologica Scandinavica microbiologica et immunologica Scandinavica, 2025-01, Vol.133 (1), p.e13485
Hauptverfasser:	Slachmuylders, E, Laenen, A, Vernemmen, A, Keupers, M, Nevelsteen, I, Han, S N, Neven, P, Van Ongeval, C, Wildiers, H, Smeets, A, Floris, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biomarkers, Tumor - metabolism Breast Neoplasms - diagnosis Breast Neoplasms - metabolism Breast Neoplasms - mortality Breast Neoplasms - pathology Diagnosis, Differential Female Fibroadenoma - diagnosis Fibroadenoma - metabolism Fibroadenoma - pathology Histones - metabolism Humans Immunohistochemistry Middle Aged Original Phyllodes Tumor - diagnosis Phyllodes Tumor - metabolism Phyllodes Tumor - pathology Phyllodes Tumor - surgery Prognosis Retrospective Studies Young Adult
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