Frailty reduces penumbral volumes and attenuates treatment response in hyperacute ischemic stroke

Frailty-the loss of physiological reserve to withstand a stressor event-is associated with poorer outcomes following acute stroke reperfusion therapies. However, the mechanisms underlying this relationship are poorly understood. This study investigated the association between frailty and penumbral v...

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Veröffentlicht in:	Age and ageing 2024-11, Vol.53 (12)
Hauptverfasser:	Dohle, Esmee, Lewis, Benjamin, Agarwal, Smriti, Warburton, Elizabeth A, Evans, Nicholas R
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Biomarkers - blood C-Reactive Protein - analysis C-Reactive Protein - metabolism Female Fibrinolytic Agents - therapeutic use Frail Elderly Frailty - complications Humans Ischemic Stroke - diagnostic imaging Ischemic Stroke - therapy Male Middle Aged Perfusion Imaging - methods Research Paper Risk Factors Severity of Illness Index Thrombolytic Therapy Time Factors Tomography, X-Ray Computed Treatment Outcome
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