Seven-year performance of a clinical metagenomic next-generation sequencing test for diagnosis of central nervous system infections

Metagenomic next-generation sequencing (mNGS) of cerebrospinal fluid (CSF) is an agnostic method for broad-based diagnosis of central nervous system (CNS) infections. Here we analyzed the 7-year performance of clinical CSF mNGS testing of 4,828 samples from June 2016 to April 2023 performed by the U...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature medicine 2024-12, Vol.30 (12), p.3522-3533
Hauptverfasser:	Benoit, Patrick, Brazer, Noah, de Lorenzi-Tognon, Mikael, Kelly, Emily, Servellita, Venice, Oseguera, Miriam, Nguyen, Jenny, Tang, Jack, Omura, Charles, Streithorst, Jessica, Hillberg, Melissa, Ingebrigtsen, Danielle, Zorn, Kelsey, Wilson, Michael R., Blicharz, Tim, Wong, Amy P., O’Donovan, Brian, Murray, Brad, Miller, Steve, Chiu, Charles Y.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/208/514/2254 692/308/575 692/699/255 692/699/375/1367 Adolescent Adult Aged Aged, 80 and over Biomedical and Life Sciences Biomedicine Cancer Research Central nervous system Central Nervous System Infections - cerebrospinal fluid Central Nervous System Infections - diagnosis Central Nervous System Infections - microbiology Central Nervous System Infections - virology Cerebrospinal fluid Child Child, Preschool Clinical microbiology Diagnosis DNA viruses Female High-Throughput Nucleotide Sequencing - methods Humans Infant Infections Infectious Diseases Laboratories Male Metabolic Diseases Metagenome - genetics Metagenomics Metagenomics - methods Microbiology Middle Aged Molecular Medicine Nervous system Neurosciences Next-generation sequencing Parasites RNA viruses Sensitivity Sensitivity analysis Sensitivity and Specificity Sequences Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!