Attenuated kidney oxidative metabolism in young adults with type 1 diabetes

BACKGROUNDIn type 1 diabetes (T1D), impaired insulin sensitivity may contribute to the development of diabetic kidney disease (DKD) through alterations in kidney oxidative metabolism.METHODSYoung adults with T1D (n = 30) and healthy controls (HCs) (n = 20) underwent hyperinsulinemic-euglycemic clamp...

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Veröffentlicht in:The Journal of clinical investigation 2024-10, Vol.134 (24)
Hauptverfasser: Choi, Ye Ji, Richard, Gabriel, Zhang, Guanshi, Hodgin, Jeffrey B, Demeke, Dawit S, Yang, Yingbao, Schaub, Jennifer A, Tamayo, Ian M, Gurung, Bhupendra K, Naik, Abhijit S, Nair, Viji, Birznieks, Carissa, MacDonald, Alexis, Narongkiatikhun, Phoom, Gross, Susan, Driscoll, Lynette, Flynn, Maureen, Tommerdahl, Kalie, Nadeau, Kristen J, Shah, Viral N, Vigers, Tim, Snell-Bergeon, Janet K, Kendrick, Jessica, van Raalte, Daniel H, Li, Lu-Ping, Prasad, Pottumarthi, Ladd, Patricia, Chin, Bennett B, Cherney, David Z, McCown, Phillip J, Alakwaa, Fadhl, Otto, Edgar A, Brosius, Frank C, Saulnier, Pierre Jean, Puelles, Victor G, Goodrich, Jesse A, Street, Kelly, Venkatachalam, Manjeri A, Ruiz, Aaron, de Boer, Ian H, Nelson, Robert G, Pyle, Laura, Blondin, Denis P, Sharma, Kumar, Kretzler, Matthias, Bjornstad, Petter
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Sprache:eng
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