Myeloid clonal hematopoiesis of indeterminate potential in patients with chronic lymphocytic leukemia

•The prevalence of myeloid CHIP in patients with CLL was 12% in untreated and 24% in treated patients (85% with prior chemotherapy exposure).•The presence of ≥2 M-CHIP mutations was associated with survival, even accounting for prior treatment and age. [Display omitted] Clonal hematopoiesis of indet...

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Veröffentlicht in:Blood advances 2024-12, Vol.8 (23), p.5949-5956
Hauptverfasser: Vijenthira, Abi, Volpe, Virginia O., Sekar, Aswin, Santos Azevedo, Roberta, Mikhaleva, Mariia, Gibson, Christopher J., Martindale, Stephen P., Fardoun, Rayan, Tyekucheva, Svitlana, Ren, Yue, Fernandes, Stacey M., Knisbacher, Binyamin A., Hahn, Cynthia K., Getz, Gad, Wu, Catherine J., Davids, Matthew S., Brown, Jennifer R.
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Sprache:eng
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