Critical Convex‐Type ST Elevation Correlate With Ventricular Tachyarrhythmia in Takotsubo Cardiomyopathy

ABSTRACT Background Ventricular tachyarrhythmia (VT) occasionally occurred in patients with Takotsubo cardiomyopathy (TC). Two convex‐type ST elevations were significantly related to VT in coronary artery disease. Methods This study assessed the correlation between VT and critical ECG patterns, as w...

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Veröffentlicht in:Clinical cardiology (Mahwah, N.J.) N.J.), 2024-12, Vol.47 (12), p.e70056-n/a
Hauptverfasser: Hsu, Jen‐Te, Hsiao, Ju‐Feng, Chin, See‐Khong, Hsu, Yu‐Cheng, Lei, Meng‐Huan
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Hsiao, Ju‐Feng
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Hsu, Yu‐Cheng
Lei, Meng‐Huan
description ABSTRACT Background Ventricular tachyarrhythmia (VT) occasionally occurred in patients with Takotsubo cardiomyopathy (TC). Two convex‐type ST elevations were significantly related to VT in coronary artery disease. Methods This study assessed the correlation between VT and critical ECG patterns, as well other independent predictive factors of in‐hospital outcome. Fifty‐five consecutive patients fulfilled the diagnostic criteria of Takotsubo Italian Network (TIN) were retrospectively enrolled. The patients were classified into two groups according to their critical ECG patterns and VT occurrence. In‐hospital outcomes and influencing factors were analyzed. Results The incidence of VT was higher in the critical ECG group than in the Noncritical ECG group (43.8% vs. 2.6%, p 
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Two convex‐type ST elevations were significantly related to VT in coronary artery disease. Methods This study assessed the correlation between VT and critical ECG patterns, as well other independent predictive factors of in‐hospital outcome. Fifty‐five consecutive patients fulfilled the diagnostic criteria of Takotsubo Italian Network (TIN) were retrospectively enrolled. The patients were classified into two groups according to their critical ECG patterns and VT occurrence. In‐hospital outcomes and influencing factors were analyzed. Results The incidence of VT was higher in the critical ECG group than in the Noncritical ECG group (43.8% vs. 2.6%, p &lt; 0.001). In‐hospital death was more common in the critical ECG group than in the Noncritical ECG group (25.0% vs. 5.1%, p = 0.032). The composite end‐point (combined VT and in‐hospital death) revealed significant differences between these two groups (50.0% vs 7.7%, p &lt; 0.001). Multi‐variate analysis proved critical ECG type as one independent risk factor of VT (odds ratio [OR] = 61.8, p = 0.009) and the composite end‐point (OR = 12.4, p = 0.007). The prolong QRS width ( ≥ 105 ms) was another independent factor for predicting VT (OR = 1.06, p = 0.022) and composite end‐point (OR = 1.05, p = 0.017). Conclusions Critical ECG types including tombstoning ST elevation and lambda‐wave ST elevation have strong impact on short‐term outcomes. Additionally, conduction disturbance with prolong QRS ≥ 105 ms also has independent predicting role for poor prognosis. Ventricular tachyarrhythmia (VT) occasionally occurred in patients with Takotsubo cardiomyopathy (TC). This study assessed the correlation between VT and critical ECG patterns. Critical ECG types including tombstoning ST elevation and lambda‐wave ST elevation have strong impact on short‐term outcomes. Summary Key findings Both critical ECG types and prolong QRS 105 ms had independent predicting role for poor prognosis in patients with stress‐induced cardiomyopathy. What is known and what is new? An lambda‐wave ST elevation and tombstoning ST elevation may predict malignant arrhythmias in patients with CAD and STEMI. For patients with stress‐induced cardiomyopathy, the critical ECG types including tombstoning ST elevation and lambda‐wave ST elevation had strong impact for VT and in‐hospital death. What is the implication, and what should change now? Above abnormal ECG signs identifying high‐risk patients and implementing close monitoring and aggressive interventions.</description><identifier>ISSN: 0160-9289</identifier><identifier>ISSN: 1932-8737</identifier><identifier>EISSN: 1932-8737</identifier><identifier>DOI: 10.1002/clc.70056</identifier><identifier>PMID: 39648966</identifier><language>eng</language><publisher>United States: John Wiley &amp; Sons, Inc</publisher><subject>Aged ; Aged, 80 and over ; Beta blockers ; Cardiac arrest ; Cardiac arrhythmia ; Cardiomyopathy ; Cardiovascular disease ; Chronic obstructive pulmonary disease ; Clinical ; convex‐type ST elevation ; Coronary vessels ; Diabetes ; Dopamine ; Edema ; Ejection fraction ; Electrocardiography ; Enzymes ; Female ; Females ; Heart Rate - physiology ; Hospital Mortality ; Hospitalization ; Humans ; Hypertension ; Incidence ; lambda‐wave ST elevation ; Male ; Middle Aged ; Patients ; Predictive Value of Tests ; Prognosis ; Retrospective Studies ; Risk Factors ; Tachycardia, Ventricular - diagnosis ; Tachycardia, Ventricular - epidemiology ; Tachycardia, Ventricular - etiology ; Tachycardia, Ventricular - mortality ; Tachycardia, Ventricular - physiopathology ; takotsubo cardiomyopathy ; Takotsubo Cardiomyopathy - complications ; Takotsubo Cardiomyopathy - diagnosis ; Takotsubo Cardiomyopathy - epidemiology ; Takotsubo Cardiomyopathy - mortality ; Takotsubo Cardiomyopathy - physiopathology ; tombstoning ST elevation ; Ventilators ; ventricular tachyarrhythmia</subject><ispartof>Clinical cardiology (Mahwah, N.J.), 2024-12, Vol.47 (12), p.e70056-n/a</ispartof><rights>2024 The Author(s). published by Wiley Periodicals, LLC.</rights><rights>2024 The Author(s). Clinical Cardiology published by Wiley Periodicals, LLC.</rights><rights>2024. This work is published under http://creativecommons.org/licenses/by/4.0/ (the "License"). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c2996-d8bbaf956e9452347fd72f1cd8e817172e347abc37e06e507dff526f2a78701c3</cites><orcidid>0000-0002-6073-102X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11626252/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11626252/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,1411,11541,27901,27902,45550,45551,46027,46451,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39648966$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hsu, Jen‐Te</creatorcontrib><creatorcontrib>Hsiao, Ju‐Feng</creatorcontrib><creatorcontrib>Chin, See‐Khong</creatorcontrib><creatorcontrib>Hsu, Yu‐Cheng</creatorcontrib><creatorcontrib>Lei, Meng‐Huan</creatorcontrib><title>Critical Convex‐Type ST Elevation Correlate With Ventricular Tachyarrhythmia in Takotsubo Cardiomyopathy</title><title>Clinical cardiology (Mahwah, N.J.)</title><addtitle>Clin Cardiol</addtitle><description>ABSTRACT Background Ventricular tachyarrhythmia (VT) occasionally occurred in patients with Takotsubo cardiomyopathy (TC). Two convex‐type ST elevations were significantly related to VT in coronary artery disease. Methods This study assessed the correlation between VT and critical ECG patterns, as well other independent predictive factors of in‐hospital outcome. Fifty‐five consecutive patients fulfilled the diagnostic criteria of Takotsubo Italian Network (TIN) were retrospectively enrolled. The patients were classified into two groups according to their critical ECG patterns and VT occurrence. In‐hospital outcomes and influencing factors were analyzed. Results The incidence of VT was higher in the critical ECG group than in the Noncritical ECG group (43.8% vs. 2.6%, p &lt; 0.001). In‐hospital death was more common in the critical ECG group than in the Noncritical ECG group (25.0% vs. 5.1%, p = 0.032). The composite end‐point (combined VT and in‐hospital death) revealed significant differences between these two groups (50.0% vs 7.7%, p &lt; 0.001). Multi‐variate analysis proved critical ECG type as one independent risk factor of VT (odds ratio [OR] = 61.8, p = 0.009) and the composite end‐point (OR = 12.4, p = 0.007). The prolong QRS width ( ≥ 105 ms) was another independent factor for predicting VT (OR = 1.06, p = 0.022) and composite end‐point (OR = 1.05, p = 0.017). Conclusions Critical ECG types including tombstoning ST elevation and lambda‐wave ST elevation have strong impact on short‐term outcomes. Additionally, conduction disturbance with prolong QRS ≥ 105 ms also has independent predicting role for poor prognosis. Ventricular tachyarrhythmia (VT) occasionally occurred in patients with Takotsubo cardiomyopathy (TC). This study assessed the correlation between VT and critical ECG patterns. Critical ECG types including tombstoning ST elevation and lambda‐wave ST elevation have strong impact on short‐term outcomes. Summary Key findings Both critical ECG types and prolong QRS 105 ms had independent predicting role for poor prognosis in patients with stress‐induced cardiomyopathy. What is known and what is new? An lambda‐wave ST elevation and tombstoning ST elevation may predict malignant arrhythmias in patients with CAD and STEMI. For patients with stress‐induced cardiomyopathy, the critical ECG types including tombstoning ST elevation and lambda‐wave ST elevation had strong impact for VT and in‐hospital death. What is the implication, and what should change now? Above abnormal ECG signs identifying high‐risk patients and implementing close monitoring and aggressive interventions.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Beta blockers</subject><subject>Cardiac arrest</subject><subject>Cardiac arrhythmia</subject><subject>Cardiomyopathy</subject><subject>Cardiovascular disease</subject><subject>Chronic obstructive pulmonary disease</subject><subject>Clinical</subject><subject>convex‐type ST elevation</subject><subject>Coronary vessels</subject><subject>Diabetes</subject><subject>Dopamine</subject><subject>Edema</subject><subject>Ejection fraction</subject><subject>Electrocardiography</subject><subject>Enzymes</subject><subject>Female</subject><subject>Females</subject><subject>Heart Rate - physiology</subject><subject>Hospital Mortality</subject><subject>Hospitalization</subject><subject>Humans</subject><subject>Hypertension</subject><subject>Incidence</subject><subject>lambda‐wave ST elevation</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Patients</subject><subject>Predictive Value of Tests</subject><subject>Prognosis</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Tachycardia, Ventricular - diagnosis</subject><subject>Tachycardia, Ventricular - epidemiology</subject><subject>Tachycardia, Ventricular - etiology</subject><subject>Tachycardia, Ventricular - mortality</subject><subject>Tachycardia, Ventricular - physiopathology</subject><subject>takotsubo cardiomyopathy</subject><subject>Takotsubo Cardiomyopathy - complications</subject><subject>Takotsubo Cardiomyopathy - diagnosis</subject><subject>Takotsubo Cardiomyopathy - epidemiology</subject><subject>Takotsubo Cardiomyopathy - mortality</subject><subject>Takotsubo Cardiomyopathy - physiopathology</subject><subject>tombstoning ST elevation</subject><subject>Ventilators</subject><subject>ventricular tachyarrhythmia</subject><issn>0160-9289</issn><issn>1932-8737</issn><issn>1932-8737</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp1kcGO0zAQhi0EYkvhwAugSFzYQ3ZtJ7HjE0LRLiBV4kCBo-U4E-LixMV2CrnxCDwjT4JLlxUgcRpp5tM__8yP0GOCLwjG9FJbfcExrtgdtCKioHnNC34XrTBhOBe0FmfoQQi7hOKaFvfRWSFYWQvGVmjXeBONVjZr3HSArz--fd8ue8jebrMrCwcVjZvSyHuwKkL2wcQhew9T9EbPVvlsq_SwKO-HJQ6jUZmZUuuTi2FuXdYo3xk3Lm6v4rA8RPd6ZQM8uqlr9O76atu8yjdvXr5uXmxyTYVgeVe3repFxUCUFS1K3nec9kR3NdSEE04h9VSrCw6YQYV51_cVZT1VvOaY6GKNnp9093M7QqePbpWVe29G5RfplJF_TyYzyI_uIAlhlNG0c42e3Sh493mGEOVoggZr1QRuDrIgJavSJwue0Kf_oDs3-yndd6Q45aUQJFHnJ0p7F4KH_tYNwfIYoUwRyl8RJvbJn_Zvyd-ZJeDyBHwxFpb_K8lm05wkfwKvi6ha</recordid><startdate>202412</startdate><enddate>202412</enddate><creator>Hsu, Jen‐Te</creator><creator>Hsiao, Ju‐Feng</creator><creator>Chin, See‐Khong</creator><creator>Hsu, Yu‐Cheng</creator><creator>Lei, Meng‐Huan</creator><general>John Wiley &amp; Sons, Inc</general><general>John Wiley and Sons Inc</general><scope>24P</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-6073-102X</orcidid></search><sort><creationdate>202412</creationdate><title>Critical Convex‐Type ST Elevation Correlate With Ventricular Tachyarrhythmia in Takotsubo Cardiomyopathy</title><author>Hsu, Jen‐Te ; Hsiao, Ju‐Feng ; Chin, See‐Khong ; Hsu, Yu‐Cheng ; Lei, Meng‐Huan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2996-d8bbaf956e9452347fd72f1cd8e817172e347abc37e06e507dff526f2a78701c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Beta blockers</topic><topic>Cardiac arrest</topic><topic>Cardiac arrhythmia</topic><topic>Cardiomyopathy</topic><topic>Cardiovascular disease</topic><topic>Chronic obstructive pulmonary disease</topic><topic>Clinical</topic><topic>convex‐type ST elevation</topic><topic>Coronary vessels</topic><topic>Diabetes</topic><topic>Dopamine</topic><topic>Edema</topic><topic>Ejection fraction</topic><topic>Electrocardiography</topic><topic>Enzymes</topic><topic>Female</topic><topic>Females</topic><topic>Heart Rate - physiology</topic><topic>Hospital Mortality</topic><topic>Hospitalization</topic><topic>Humans</topic><topic>Hypertension</topic><topic>Incidence</topic><topic>lambda‐wave ST elevation</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Patients</topic><topic>Predictive Value of Tests</topic><topic>Prognosis</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Tachycardia, Ventricular - diagnosis</topic><topic>Tachycardia, Ventricular - epidemiology</topic><topic>Tachycardia, Ventricular - etiology</topic><topic>Tachycardia, Ventricular - mortality</topic><topic>Tachycardia, Ventricular - physiopathology</topic><topic>takotsubo cardiomyopathy</topic><topic>Takotsubo Cardiomyopathy - complications</topic><topic>Takotsubo Cardiomyopathy - diagnosis</topic><topic>Takotsubo Cardiomyopathy - epidemiology</topic><topic>Takotsubo Cardiomyopathy - mortality</topic><topic>Takotsubo Cardiomyopathy - physiopathology</topic><topic>tombstoning ST elevation</topic><topic>Ventilators</topic><topic>ventricular tachyarrhythmia</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hsu, Jen‐Te</creatorcontrib><creatorcontrib>Hsiao, Ju‐Feng</creatorcontrib><creatorcontrib>Chin, See‐Khong</creatorcontrib><creatorcontrib>Hsu, Yu‐Cheng</creatorcontrib><creatorcontrib>Lei, Meng‐Huan</creatorcontrib><collection>Wiley Online Library Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health &amp; 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Two convex‐type ST elevations were significantly related to VT in coronary artery disease. Methods This study assessed the correlation between VT and critical ECG patterns, as well other independent predictive factors of in‐hospital outcome. Fifty‐five consecutive patients fulfilled the diagnostic criteria of Takotsubo Italian Network (TIN) were retrospectively enrolled. The patients were classified into two groups according to their critical ECG patterns and VT occurrence. In‐hospital outcomes and influencing factors were analyzed. Results The incidence of VT was higher in the critical ECG group than in the Noncritical ECG group (43.8% vs. 2.6%, p &lt; 0.001). In‐hospital death was more common in the critical ECG group than in the Noncritical ECG group (25.0% vs. 5.1%, p = 0.032). The composite end‐point (combined VT and in‐hospital death) revealed significant differences between these two groups (50.0% vs 7.7%, p &lt; 0.001). Multi‐variate analysis proved critical ECG type as one independent risk factor of VT (odds ratio [OR] = 61.8, p = 0.009) and the composite end‐point (OR = 12.4, p = 0.007). The prolong QRS width ( ≥ 105 ms) was another independent factor for predicting VT (OR = 1.06, p = 0.022) and composite end‐point (OR = 1.05, p = 0.017). Conclusions Critical ECG types including tombstoning ST elevation and lambda‐wave ST elevation have strong impact on short‐term outcomes. Additionally, conduction disturbance with prolong QRS ≥ 105 ms also has independent predicting role for poor prognosis. Ventricular tachyarrhythmia (VT) occasionally occurred in patients with Takotsubo cardiomyopathy (TC). This study assessed the correlation between VT and critical ECG patterns. Critical ECG types including tombstoning ST elevation and lambda‐wave ST elevation have strong impact on short‐term outcomes. Summary Key findings Both critical ECG types and prolong QRS 105 ms had independent predicting role for poor prognosis in patients with stress‐induced cardiomyopathy. What is known and what is new? An lambda‐wave ST elevation and tombstoning ST elevation may predict malignant arrhythmias in patients with CAD and STEMI. For patients with stress‐induced cardiomyopathy, the critical ECG types including tombstoning ST elevation and lambda‐wave ST elevation had strong impact for VT and in‐hospital death. What is the implication, and what should change now? Above abnormal ECG signs identifying high‐risk patients and implementing close monitoring and aggressive interventions.</abstract><cop>United States</cop><pub>John Wiley &amp; Sons, Inc</pub><pmid>39648966</pmid><doi>10.1002/clc.70056</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0002-6073-102X</orcidid><oa>free_for_read</oa></addata></record>
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source MEDLINE; Wiley Online Library Open Access; DOAJ Directory of Open Access Journals; Wiley Online Library Journals Frontfile Complete; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central
subjects Aged
Aged, 80 and over
Beta blockers
Cardiac arrest
Cardiac arrhythmia
Cardiomyopathy
Cardiovascular disease
Chronic obstructive pulmonary disease
Clinical
convex‐type ST elevation
Coronary vessels
Diabetes
Dopamine
Edema
Ejection fraction
Electrocardiography
Enzymes
Female
Females
Heart Rate - physiology
Hospital Mortality
Hospitalization
Humans
Hypertension
Incidence
lambda‐wave ST elevation
Male
Middle Aged
Patients
Predictive Value of Tests
Prognosis
Retrospective Studies
Risk Factors
Tachycardia, Ventricular - diagnosis
Tachycardia, Ventricular - epidemiology
Tachycardia, Ventricular - etiology
Tachycardia, Ventricular - mortality
Tachycardia, Ventricular - physiopathology
takotsubo cardiomyopathy
Takotsubo Cardiomyopathy - complications
Takotsubo Cardiomyopathy - diagnosis
Takotsubo Cardiomyopathy - epidemiology
Takotsubo Cardiomyopathy - mortality
Takotsubo Cardiomyopathy - physiopathology
tombstoning ST elevation
Ventilators
ventricular tachyarrhythmia
title Critical Convex‐Type ST Elevation Correlate With Ventricular Tachyarrhythmia in Takotsubo Cardiomyopathy
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