Molecular insights into the structure and function of the Staphylococcus aureus fatty acid kinase

Gram-positive bacteria utilize a Fatty Acid Kinase (FAK) complex to harvest fatty acids from the environment. This complex consists of the fatty acid kinase, FakA, and an acyl carrier protein, FakB, and is known to impact virulence and disease outcomes. Despite some recent studies, there remain many...

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Veröffentlicht in:	The Journal of biological chemistry 2024-12, Vol.300 (12), p.107920, Article 107920
Hauptverfasser:	Myers, Megan J., Xu, Zhen, Ryan, Benjamin J., DeMars, Zachary R., Ridder, Miranda J., Johnson, David K., Krute, Christina N., Flynn, Tony S., Kashipathy, Maithri M., Battaile, Kevin P., Schnicker, Nicholas, Lovell, Scott, Freudenthal, Bret D., Bose, Jeffrey L.
Format:	Artikel
Sprache:	eng
Schlagworte:	fatty acid binding protein fatty acid kinase fatty acid metabolism kinase membrane MRSA proline isomerization protein-protein interaction Staphylococcus aureus (S. aureus)
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