NMR Screen Reveals the Diverse Structural Landscape of a G‐Quadruplex Library

G‐quadruplexes are noncanonical nucleic acid structures formed by stacked guanosine tetrads. Despite their functional and structural diversity, a single consensus model is typically used to describe sequences with the potential to form G‐quadruplex structures. We are interested in developing more sp...

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Veröffentlicht in:	Chemistry : a European journal 2024-12, Vol.30 (67), p.e202401437-n/a
Hauptverfasser:	Sgallová, Ráchel, Volek, Martin, Kurfürst, Jaroslav, Srb, Pavel, Veverka, Václav, Curtis, Edward A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Conserved sequence DNA Functionals G-quadruplex G-Quadruplexes Guanosine Triphosphate - chemistry Guanosine Triphosphate - metabolism Libraries Magnetic Resonance Spectroscopy - methods Multimeric structures Mutation NMR Nuclear magnetic resonance Nucleic acids Peroxidase Sequences Spectra Structure-function relationships Tetrads
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