Glutamate as a candidate retrograde messenger at interneurone-Purkinje cell synapses of rat cerebellum

1. Depolarization-induced suppression of inhibition (DSI) is a form of synaptic plasticity which involves a retrograde messenger. We have performed experiments in Purkinje cells of rat cerebellar slices to determine the nature of this messenger. 2. DSI is mimicked by 2-(2,3-dicarboxycyclopropyl)-gly...

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Veröffentlicht in:	The Journal of physiology 1996-12, Vol.497 (Pt 2), p.531-537
Hauptverfasser:	Glitsch, M, Llano, I, Marty, A
Format:	Artikel
Sprache:	eng
Schlagworte:	2-Amino-5-phosphonovalerate - pharmacology Alanine - analogs & derivatives Alanine - pharmacology Animals Benzoates - pharmacology Colforsin - pharmacology Cyclopropanes - pharmacology Electrophysiology Excitatory Amino Acid Antagonists - pharmacology Glutamic Acid - physiology Glycine - analogs & derivatives Glycine - pharmacology Interneurons - chemistry Interneurons - physiology Kinetics Presynaptic Terminals - chemistry Presynaptic Terminals - physiology Purkinje Cells - chemistry Purkinje Cells - physiology Purkinje Cells - ultrastructure Quinoxalines - pharmacology Rats Receptors, Metabotropic Glutamate - agonists Receptors, Metabotropic Glutamate - antagonists & inhibitors Receptors, Metabotropic Glutamate - physiology Synapses - chemistry Synapses - drug effects Synapses - physiology Synaptic Transmission - drug effects Synaptic Transmission - physiology Tetrodotoxin - pharmacology
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