Non-apoptotic caspase events and Atf3 expression underlie direct neuronal differentiation of adult neural stem cells

Neural stem cells (NSCs) generate neurons over a lifetime in adult vertebrate brains. In the adult zebrafish pallium, NSCs persist long term through balanced fate decisions. These decisions include direct neuronal conversions, i.e. delamination and neurogenesis without a division. To characterize th...

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Veröffentlicht in:	Development (Cambridge) 2024-11, Vol.151 (22)
Hauptverfasser:	Rosa, Frédéric, Dray, Nicolas, Bedu, Sébastien, Bally-Cuif, Laure
Format:	Artikel
Sprache:	eng
Schlagworte:	Activating Transcription Factor 3 - genetics Activating Transcription Factor 3 - metabolism Adult Stem Cells - cytology Adult Stem Cells - metabolism Animals Apoptosis Caspase 3 - metabolism Caspase 7 - genetics Caspase 7 - metabolism Caspases - metabolism Cell Differentiation Cell Lineage Neural Stem Cells - cytology Neural Stem Cells - metabolism Neurogenesis - genetics Neurons - cytology Neurons - metabolism Zebrafish - metabolism Zebrafish Proteins - genetics Zebrafish Proteins - metabolism
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