The Cough Response to Inhaled Mannitol in Healthy Subjects

Purpose Inhaled mannitol induces bronchoconstriction and cough. This study aimed to describe the cough response to mannitol among healthy adult subjects. Methods 125 healthy subjects (aged 18–82 years, 52% females, 50% skin prick test positive) underwent a mannitol test. The coughs were recorded bot...

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Veröffentlicht in:	Lung 2025-12, Vol.203 (1), p.5-5, Article 5
Hauptverfasser:	Nurmi, Hanna M., Lätti, Anne M., Koskela, Heikki O.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Inhalation Adolescent Adult adults Aged Aged, 80 and over Bronchial Provocation Tests - methods Bronchoconstriction Bronchoconstriction - drug effects Correlation coefficient Correlation coefficients Cough Cough - physiopathology Female Females gender Healthy Volunteers Humans lungs Male Mannitol Mannitol - administration & dosage Medicine Medicine & Public Health Middle Aged NCT NCT05034367 Pneumology/Respiratory System Reproducibility Reproducibility of Results Sex Factors skin prick tests Skin tests Statistical analysis Threshold limits Young Adult
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