Integrating continuous flow reaction and work-up: chiral amine resolution, separation and purification using a novel coalescing filter system

To maximize the benefits of a continuous flow reaction, a continuous work-up is also needed. Herein, we present a process design and novel equipment for a continuous amine resolution reaction, integrated with liquid-liquid (L-L) extraction, back-extraction into a different solvent, and crystallisati...

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Veröffentlicht in:Reaction chemistry & engineering 2024-11
Hauptverfasser: Rowley, Bethan M, Thompson, Lisa A, Power, Luke A, Daglish, James, Parks, Emma, Birbeck, James, Marsden, Steve, Kapur, Nikil, Blacker, A John
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Sprache:eng
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