Distinct fingerprints of tRNA-derived small non-coding RNA in animal models of neurodegeneration

Transfer RNA-derived small RNAs (tsRNAs) - categorized as tRNA-derived fragments (tRFs), tRNA-derived stress-induced RNAs (tiRNAs) and internal tRF (itRF) - are small non-coding RNAs that participate in various cellular processes such as translation inhibition and responses to cellular stress. We he...

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Veröffentlicht in:	Disease models & mechanisms 2024-11, Vol.17 (11)
Hauptverfasser:	Baindoor, Sharada, Gibriel, Hesham A Y, Venø, Morten T, Su, Junyi, Morrissey, Elena Perez, Jirström, Elisabeth, Woods, Ina, Kenny, Aidan, Alves, Mariana, Halang, Luise, Fabbrizio, Paola, Bilen, Maria, Engel, Tobias, Hogg, Marion C, Bendotti, Caterina, Nardo, Giovanni, Slack, Ruth S, Kjems, Jørgen, Prehn, Jochen H M
Format:	Artikel
Sprache:	eng
Schlagworte:	amyotrophic lateral sclerosis Amyotrophic Lateral Sclerosis - genetics Amyotrophic Lateral Sclerosis - pathology Animals Disease Models, Animal frontotemporal dementia Frontotemporal Dementia - genetics Frontotemporal Dementia - pathology Humans Mice Mice, Transgenic Neurodegenerative Diseases - genetics Neurodegenerative Diseases - pathology Parkinson Disease - genetics Parkinson Disease - pathology parkinson's disease RNA, Small Untranslated - genetics RNA, Transfer - genetics RNA, Transfer - metabolism tirna trf tsrna
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