JCat: a novel tool to adapt codon usage of a target gene to its potential expression host

A novel method for the adaptation of target gene codon usage to most sequenced prokaryotes and selected eukaryotic gene expression hosts was developed to improve heterologous protein production. In contrast to existing tools, JCat (Java Codon Adaptation Tool) does not require the manual definition o...

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Veröffentlicht in:	Nucleic acids research 2005-07, Vol.33 (suppl-2), p.W526-W531
Hauptverfasser:	Grote, Andreas, Hiller, Karsten, Scheer, Maurice, Münch, Richard, Nörtemann, Bernd, Hempel, Dietmar C., Jahn, Dieter
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Animals Caenorhabditis elegans Caenorhabditis elegans - genetics Codon Escherichia coli Escherichia coli - genetics Gene Expression Internet Pseudomonas aeruginosa Pseudomonas aeruginosa - genetics Recombinant Proteins - biosynthesis Recombinant Proteins - genetics Software Species Specificity User-Computer Interface
Online-Zugang:	Volltext
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