Neuroprotective Effects of Ethanol Extract Polyscias guilfoylei (EEPG) Against Glutamate Induced Neurotoxicity in HT22 Cells

Oxidative stress induced by glutamate is a significant contributor to neuronal cell damage and can lead to neurodegenerative diseases such as Alzheimer's, Huntington's, and ischemic brain injury. At the cellular level, oxidative stress increases Ca ion influx and reactive oxygen species (R...

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Veröffentlicht in:	International journal of molecular sciences 2024-11, Vol.25 (22), p.12153
Hauptverfasser:	Nguyen, Qui Ngoc Sang, Yoo, Ki-Yeon, Pham, Thi Thu Trang, Selvaraj, Baskar, Vu, Huong Thuy, Le, Tam Thi, Lee, Heesu, Tran, Quang Luc, Thuong, Phuong Thien, Pae, Ae Nim, Jung, Sang Hoon, Lee, Jae Wook
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetaldehyde Alcohol Alcohol, Denatured Amino acids Analysis Animals Antioxidants Apoptosis Apoptosis - drug effects Araliaceae - chemistry Brain Brain Ischemia - drug therapy Brain Ischemia - metabolism Calcium - metabolism Cell death Cell Line Cell Survival - drug effects Ethanol Ethanol - toxicity Glutamate Glutamic Acid - metabolism Glutamic Acid - toxicity Herbal medicine Injuries Ischemia Kinases Male Mice Nervous system diseases Neurons Neurons - drug effects Neurons - metabolism Neuroprotective Agents - pharmacology Neurotoxicity Older people Oxidative stress Oxidative Stress - drug effects Plant Extracts - pharmacology Proteins Rats Reactive oxygen species Reactive Oxygen Species - metabolism Stroke Traumatic brain injury
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