pH gradient effects on chloride transport across basolateral membrane vesicles from guinea-pig jejunum

1. The effects of alkaline-inside pH gradients on 36Cl- uptake were quantified by using brush-border membrane (BBM) and basolateral membrane (BLM) vesicles from guinea-pig jejunum. 2. With BBM vesicles, a pHo/pHi gradient of 5.0/7.5 yielded fast overshoots involving a random, non-obligatory Cl(-)-H+...

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Veröffentlicht in:	The Journal of physiology 1997-04, Vol.500 (Pt 2), p.385-400
Hauptverfasser:	Touzani, K, Alvarado, F, Vasseur, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arylsulfonates Carbonyl Cyanide m-Chlorophenyl Hydrazone - pharmacology Cell Membrane - chemistry Cell Membrane - drug effects Cell Membrane - metabolism Chloride Channels - metabolism Chlorides - pharmacokinetics Fluorescent Dyes Guinea Pigs Hydrogen-Ion Concentration Ionophores - pharmacology Jejunum - metabolism Jejunum - ultrastructure Kinetics Membrane Potentials - physiology Microvilli - chemistry Microvilli - metabolism Potassium - metabolism Protons Time Factors Valinomycin - pharmacology
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