Discovery of RNA Biomarkers for Prostate Cancer Using Cross-Platform Transcriptomics

Microarray and Single-Molecule Molecular Inversion Probe (smMIP)-based targeted RNA sequencing are two RNA profiling platforms for identifying disease-associated biomarkers. The microarray uses a GeneChip array with oligonucleotide probes to measure expression levels across thousands of genes, while...

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Veröffentlicht in:	International journal of molecular sciences 2024-11, Vol.25 (22), p.11907
Hauptverfasser:	Visser, Wieke C H, de Jong, Hans, Smit, Frank P, Shrivastava, Jolly, Poole, Jason C, Leenders, William P J, Melchers, Willem J G, Mulders, Peter F A, Schalken, Jack A
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological markers Biomarkers Biomarkers, Tumor - genetics DNA microarrays Gene expression Gene Expression Profiling - methods Gene Expression Regulation, Neoplastic Genes High-Throughput Nucleotide Sequencing - methods Humans Male Methods Mutation Oligonucleotide Array Sequence Analysis - methods Prostate cancer Prostatic Hyperplasia - genetics Prostatic Hyperplasia - metabolism Prostatic Neoplasms - genetics Prostatic Neoplasms - metabolism RNA RNA - genetics RNA sequencing Sequence Analysis, RNA - methods Transcriptome
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