Sensitive Detection of Gynecological Cancer Recurrence Using Circulating Tumor DNA and Digital PCR: A Comparative Study with Serum Biochemical Markers

Early detection of recurrences in gynecological cancers is crucial for women's health. Circulating tumor DNA (ctDNA) analysis through liquid biopsy offers a promising approach for monitoring disease progression and identifying relapses. This study investigated the utility of digital Polymerase...

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Veröffentlicht in:	International journal of molecular sciences 2024-11, Vol.25 (22), p.11997
Hauptverfasser:	Balasan, Nour, Kharrat, Feras, Di Lorenzo, Giovanni, Athanasakis, Emmanouil, Bianco, Anna Monica, Conti, Andrea, Di Stazio, Maria Teresa, Butera, Giulia, Cicogna, Stefania, Mangogna, Alessandro, Romano, Federico, Ricci, Giuseppe, d'Adamo, Adamo Pio
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants Aged Antigens Biomarkers, Tumor - blood Biomarkers, Tumor - genetics Biopsy Cancer therapies Chemotherapy Circulating Tumor DNA - blood Circulating Tumor DNA - genetics Endometrial cancer Female Genital Neoplasms, Female - blood Genital Neoplasms, Female - diagnosis Genital Neoplasms, Female - genetics Gynecological cancer Humans Laparoscopy Liquid Biopsy - methods Metastasis Middle Aged Mutation Neoplasm Recurrence, Local - blood Neoplasm Recurrence, Local - genetics Ovarian cancer Patients Plasma Polymerase Chain Reaction - methods Surgery Tomography Tumors
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