Dynamic changes in fat oxidation in human primary myocytes mirror metabolic characteristics of the donor

Metabolic flexibility of skeletal muscle, that is, the preference for fat oxidation (FOx) during fasting and for carbohydrate oxidation in response to insulin, is decreased during insulin resistance. The aim of this study was to test the hypothesis that the capacity of myotubes to oxidize fat in vit...

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Veröffentlicht in:	The Journal of clinical investigation 2005-07, Vol.115 (7), p.1934-1941
Hauptverfasser:	Ukropcova, Barbara, McNeil, Michele, Sereda, Olga, de Jonge, Lilian, Xie, Hui, Bray, George A, Smith, Steven R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Biomedical research Dietary Fats - metabolism Glucose - metabolism Glucose Clamp Technique Humans In Vitro Techniques Insulin Resistance Male Models, Biological Muscle Fibers, Skeletal - metabolism Oxidation-Reduction Palmitic Acid - metabolism Phenotype
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