Lymphocytes induce resorption of cartilage by producing catabolin

Mononuclear cells from pig blood, when cultured in the presence of lectins (concanavalin A or phytohaemagglutinin), release a factor that induces resorption of proteoglycan in explants of live bovine nasal cartilage. The factor had mol.wt. 20000 and pI 4.6-5.0, and was indistinguishable from the car...

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Veröffentlicht in:	Biochemical journal 1982-01, Vol.202 (1), p.275-278
Hauptverfasser:	Saklatvala, J, Sarsfield, S J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood Proteins Cartilage - drug effects Cartilage - metabolism Cells, Cultured Hydrocortisone - pharmacology Interleukin-1 Interleukin-1beta Lymphocytes - metabolism Proteins - pharmacology Proteoglycans - metabolism Swine
Online-Zugang:	Volltext
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