Arachidonic acid activation of a new family of K+ channels in cultured rat neuronal cells

1. The presence and properties of K+ channels activated by arachidonic acid were studied in neuronal cells cultured from the mesencephalic and hypothalamic areas of rat brain. 2. Arachidonic acid produced a concentration-dependent (5-50 microM) and reversible activation of whole-cell currents. 3. In...

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Veröffentlicht in:	The Journal of physiology 1995-05, Vol.484 (Pt 3), p.643-660
Hauptverfasser:	Kim, D, Sladek, C D, Aguado-Velasco, C, Mathiasen, J R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arachidonic Acid - pharmacology Cells, Cultured Electric Conductivity Fatty Acids - metabolism Glutamic Acid - pharmacology Hydrogen-Ion Concentration Ions Mechanoreceptors - physiology Neurons - drug effects Neurons - physiology Osmolar Concentration Potassium Channels - drug effects Potassium Channels - physiology Rats Rats, Sprague-Dawley Space life sciences
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