Enantioselective Preparation of Cyclopentene-Based Amino Acids with a Quaternary Carbon Center

Azlactone is an important starting material for synthesizing amino acids containing a quaternary α-carbon. In this study, we have developed a sequential “one-pot” procedure involving an enantioselective spirocyclization reaction followed by acidic azlactone opening, which led to amino acid derivativ...

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Veröffentlicht in:	Journal of organic chemistry 2024-11, Vol.89 (22), p.16522-16530
Hauptverfasser:	Franc, Michael, Měrka, Pavel, Císařová, Ivana, Veselý, Jan
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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