Chemical composition and pharmacological aspects of Malaysian stingless bee propolis: An up‑to‑date systematic review
Propolis is a sticky substance produced by stingless bees for construction and defence of their hive. It has notable anti-inflammatory, antioxidant, antibacterial, antifungal, anti-hyperglycemic, and wound healing effects. The present review summarised and examined the phytochemical properties, mode...
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Veröffentlicht in: | Biomedical reports 2025-01, Vol.22 (1), p.9, Article 9 |
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creator | Jusril, Nor Atiqah Mohd, Khamsah Suryati Abd Mutalib, Nurliana Mohd Badiazaman, Ainur Awanis |
description | Propolis is a sticky substance produced by stingless bees for construction and defence of their hive. It has notable anti-inflammatory, antioxidant, antibacterial, antifungal, anti-hyperglycemic, and wound healing effects. The present review summarised and examined the phytochemical properties, mode of action and current research prospects of Malaysian propolis. A database search using Google Scholar, Web of Science and ScienceDirect generated 780 references; 30 relevant articles were included in the present review, of which 23 were
studies and 7 were
or animal studies. Propolis demonstrated antioxidant, antibacterial, antifungal, anti-inflammatory and anti-hyperglycemic properties, indicating potential as a wound healing agent. Despite favourable findings, due to the scarcity of studies in the literature, more in-depth research and clinical validation on the synergistic effects, efficacy and optimum dosage of propolis are needed. |
doi_str_mv | 10.3892/br.2024.1887 |
format | Article |
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studies and 7 were
or animal studies. Propolis demonstrated antioxidant, antibacterial, antifungal, anti-inflammatory and anti-hyperglycemic properties, indicating potential as a wound healing agent. Despite favourable findings, due to the scarcity of studies in the literature, more in-depth research and clinical validation on the synergistic effects, efficacy and optimum dosage of propolis are needed.</description><identifier>ISSN: 2049-9434</identifier><identifier>ISSN: 2049-9442</identifier><identifier>EISSN: 2049-9442</identifier><identifier>DOI: 10.3892/br.2024.1887</identifier><identifier>PMID: 39559820</identifier><language>eng</language><publisher>England: Spandidos Publications UK Ltd</publisher><subject>Antiinfectives and antibacterials ; Antimicrobial agents ; Antioxidants ; Apoptosis ; Beehives ; Breast cancer ; Chemical composition ; Chemical compounds ; Cytotoxicity ; Drug dosages ; Fungicides ; In vivo methods and tests ; Inflammation ; Morphology ; Pharmaceuticals ; Propolis ; Reviews ; Science ; Synergistic effect ; Systematic review ; Toxicity ; Wound healing</subject><ispartof>Biomedical reports, 2025-01, Vol.22 (1), p.9, Article 9</ispartof><rights>Copyright: © 2024 Jusril et al.</rights><rights>Copyright Spandidos Publications UK Ltd. 2025</rights><rights>Copyright: © 2024 Jusril et al. 2024</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c300t-10f796102cfe20d45f2abd6022df582bec6553a4b194b1c6f6289c77d1ec0d4b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11572029/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11572029/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,728,781,785,886,27928,27929,53795,53797</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39559820$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jusril, Nor Atiqah</creatorcontrib><creatorcontrib>Mohd, Khamsah Suryati</creatorcontrib><creatorcontrib>Abd Mutalib, Nurliana</creatorcontrib><creatorcontrib>Mohd Badiazaman, Ainur Awanis</creatorcontrib><title>Chemical composition and pharmacological aspects of Malaysian stingless bee propolis: An up‑to‑date systematic review</title><title>Biomedical reports</title><addtitle>Biomed Rep</addtitle><description>Propolis is a sticky substance produced by stingless bees for construction and defence of their hive. It has notable anti-inflammatory, antioxidant, antibacterial, antifungal, anti-hyperglycemic, and wound healing effects. The present review summarised and examined the phytochemical properties, mode of action and current research prospects of Malaysian propolis. A database search using Google Scholar, Web of Science and ScienceDirect generated 780 references; 30 relevant articles were included in the present review, of which 23 were
studies and 7 were
or animal studies. Propolis demonstrated antioxidant, antibacterial, antifungal, anti-inflammatory and anti-hyperglycemic properties, indicating potential as a wound healing agent. Despite favourable findings, due to the scarcity of studies in the literature, more in-depth research and clinical validation on the synergistic effects, efficacy and optimum dosage of propolis are needed.</description><subject>Antiinfectives and antibacterials</subject><subject>Antimicrobial agents</subject><subject>Antioxidants</subject><subject>Apoptosis</subject><subject>Beehives</subject><subject>Breast cancer</subject><subject>Chemical composition</subject><subject>Chemical compounds</subject><subject>Cytotoxicity</subject><subject>Drug dosages</subject><subject>Fungicides</subject><subject>In vivo methods and tests</subject><subject>Inflammation</subject><subject>Morphology</subject><subject>Pharmaceuticals</subject><subject>Propolis</subject><subject>Reviews</subject><subject>Science</subject><subject>Synergistic effect</subject><subject>Systematic review</subject><subject>Toxicity</subject><subject>Wound healing</subject><issn>2049-9434</issn><issn>2049-9442</issn><issn>2049-9442</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2025</creationdate><recordtype>article</recordtype><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNpdkctuFDEQRVsIRKKQHWtkiQ0LZvCrH2aDohEvKYgNrC23u3rGkdtuXO5Es-MX-MV8STwkjABLZZdUR1d1favqOaNr0Sn-pk9rTrlcs65rH1WnnEq1UlLyx8deyJPqHPGKlqNayuvuaXUiVF2rjtPTar_ZweSs8cTGaY7osouBmDCQeWfSZGz0cft7bnAGm5HEkXwx3uzRmUAwu7D1gEh6ADKnOEfv8C25CGSZb3_-yrFcg8lAcI8ZJpOdJQmuHdw8q56MxiOcP7xn1fcP779tPq0uv378vLm4XFlBaV4xOraqYZTbETgdZD1y0w8N5XwY6473YJu6Fkb2TJWyzdjwTtm2HRjYgvfirHp3rzsv_QSDhZCT8XpObjJpr6Nx-t9JcDu9jdeasbotn6uKwqsHhRR_LIBZTw4teG8CxAW1YIJyxgTvCvryP_QqLikUf4WSnLVKqqZQr-8pmyJigvG4DaP6kKvukz7kqg-5FvzF3w6O8J8UxR07n6JT</recordid><startdate>20250101</startdate><enddate>20250101</enddate><creator>Jusril, Nor Atiqah</creator><creator>Mohd, Khamsah Suryati</creator><creator>Abd Mutalib, Nurliana</creator><creator>Mohd Badiazaman, Ainur Awanis</creator><general>Spandidos Publications UK Ltd</general><general>D.A. 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It has notable anti-inflammatory, antioxidant, antibacterial, antifungal, anti-hyperglycemic, and wound healing effects. The present review summarised and examined the phytochemical properties, mode of action and current research prospects of Malaysian propolis. A database search using Google Scholar, Web of Science and ScienceDirect generated 780 references; 30 relevant articles were included in the present review, of which 23 were
studies and 7 were
or animal studies. Propolis demonstrated antioxidant, antibacterial, antifungal, anti-inflammatory and anti-hyperglycemic properties, indicating potential as a wound healing agent. Despite favourable findings, due to the scarcity of studies in the literature, more in-depth research and clinical validation on the synergistic effects, efficacy and optimum dosage of propolis are needed.</abstract><cop>England</cop><pub>Spandidos Publications UK Ltd</pub><pmid>39559820</pmid><doi>10.3892/br.2024.1887</doi><oa>free_for_read</oa></addata></record> |
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source | Spandidos Publications Journals; EZB-FREE-00999 freely available EZB journals; PubMed Central |
subjects | Antiinfectives and antibacterials Antimicrobial agents Antioxidants Apoptosis Beehives Breast cancer Chemical composition Chemical compounds Cytotoxicity Drug dosages Fungicides In vivo methods and tests Inflammation Morphology Pharmaceuticals Propolis Reviews Science Synergistic effect Systematic review Toxicity Wound healing |
title | Chemical composition and pharmacological aspects of Malaysian stingless bee propolis: An up‑to‑date systematic review |
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