Conjugation Mediates Large-Scale Chromosomal Transfer in Streptomyces Driving Diversification of Antibiotic Biosynthetic Gene Clusters

Abstract Streptomyces are ubiquitous soil-dwelling bacteria with large, linear genomes that are of special importance as a source of metabolites used in human and veterinary medicine, agronomy, and industry. Conjugative elements (actinomycetes integrative and conjugative elements, AICEs) are the mai...

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Veröffentlicht in:Molecular biology and evolution 2024-11, Vol.41 (11)
Hauptverfasser: Choufa, Caroline, Gascht, Pauline, Leblond, Hugo, Gauthier, Anthony, Vos, Michiel, Bontemps, Cyril, Leblond, Pierre
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Sprache:eng
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