Further Evidence for Strong Nonneutrality of Yeast Synonymous Mutations

Abstract Although synonymous mutations are commonly assumed neutral or nearly so, recent years have seen reports of fitness effects of synonymous mutations detected under laboratory conditions. In a previous study, we used genome editing to construct thousands of yeast mutants each carrying a synony...

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Veröffentlicht in:Molecular biology and evolution 2024-11, Vol.41 (11)
Hauptverfasser: Shen, Xukang, Song, Siliang, Li, Chuan, Zhang, Jianzhi
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Sprache:eng
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