Favorable inhibitory effect of clodronate on hepatic steatosis in short bowel syndrome model rats

Purpose This study investigated the anti-inflammatory effect of clodronate, a vesicular nucleotide transporter (VNUT) inhibitor, on intestinal-failure-associated liver disease (IFALD) in a rat model of short bowel syndrome (SBS). Methods The rats underwent jugular vein catheterization for continuous...

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Veröffentlicht in:	Pediatric surgery international 2024-11, Vol.40 (1), p.307, Article 307
Hauptverfasser:	Tsuruno, Yudai, Nagano, Ayaka, Sugita, Koshiro, Onishi, Shun, Tabata, Yumiko, Kedoin, Chihiro, Murakami, Masakazu, Yano, Keisuke, Kawano, Takafumi, Hasuzawa, Nao, Nomura, Masatoshi, Kaji, Tatsuru, Bitoh, Yuko, Ieiri, Satoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Catheters Clodronic Acid - therapeutic use Cytokines Disease Models, Animal Drug dosages Fatty Liver Inflammation Intubation Laboratory animals Lipids Liver - drug effects Liver - pathology Liver diseases Male Medical research Medicine Medicine & Public Health Metabolism Nutrition Original Original Article Parenteral nutrition Pediatric Surgery Pediatrics Polymerase chain reaction Rats Rats, Sprague-Dawley Short Bowel Syndrome - complications Small intestine Surgery Tumor necrosis factor-TNF
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