Iodine Bioavailability and Biochemical Effects of Brassica oleracea var. sabellica L. Biofortified with 8-Hydroxy-7-iodo-5-quinolinesulfonic Acid in Wistar Rats
Iodine is one of the essential trace elements for human life. The main objective of the biofortification of plants with iodine is to obtain food with a higher content of this element compared to conventional food. Biofortification of plants with iodine can increase the intake of this trace element b...
Gespeichert in:
| Veröffentlicht in: | Nutrients 2024-10, Vol.16 (21), p.3578 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 21 |
| container_start_page | 3578 |
| container_title | Nutrients |
| container_volume | 16 |
| creator | Krzemińska, Joanna Piątkowska, Ewa Kopeć, Aneta Smoleń, Sylwester Leszczyńska, Teresa Koronowicz, Aneta |
| description | Iodine is one of the essential trace elements for human life. The main objective of the biofortification of plants with iodine is to obtain food with a higher content of this element compared to conventional food. Biofortification of plants with iodine can increase the intake of this trace element by different populations. In addition, it may reduce the risk of iodine deficiency diseases.
The aim of the study was to investigate the effect of kale biofortified with 8-hydroxy-7-iodo-5-quinolinesulfonic acid (8-OH-7-I-5QSA) on iodine bioavailability and biochemical effects in Wistar rats.
Kale biofortified with (8-OH-7-I-5QSA) was tested for iodine levels in urine, feces, and selected tissues using the ICP-MS/MS technique. The feeding experiment was designed to investigate potential changes in selected thyroid-regulated biochemical parameters in blood serum of Wistar rats.
The dietary intake of Wistar rats fed kale biofortified with (8-OH-7-I-5QSA) from both the "Oldenbor F
" and "Redbor F
" cultivars for 8 weeks resulted in significantly (
≤ 0.05) higher iodine concentrations in the urine and kidneys of rats, which proves iodine bioavailability. Rats' diets with "Oldenbor F
" and "Redbor F
" kale non- and -biofortified with 8-OH-7-I-5QSA had a significantly (
≤ 0.05) lower or a tendency for lower concentration of TSH, triglyceride, total and direct bilirubin, TBARs, uric acid, aspartate aminotransferase (AST) and alanine aminotransferase (ALT) concentrations in serum. Dietary intake of "Oldenbor F
" and "Redbor F
" kale biofortified with 8-OH-7-I-5QSA significantly (
≤ 0.05) increased the total antioxidant status (TAS).
Our study confirms that kale biofortified with iodine in organic form iodoquinoline 8-OH-7-I-5QSA is bioavailable and well absorbed by the Wistar rat and has a positive effect on selected biochemical parameters. The results obtained in this study may be highly predictive for further studies in humans. |
| doi_str_mv | 10.3390/nu16213578 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11547991</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A815420808</galeid><sourcerecordid>A815420808</sourcerecordid><originalsourceid>FETCH-LOGICAL-c327t-81750639fdd0aa97869c7ea7849cc162de807a1ec1f49ca19244dabdc5c5ade13</originalsourceid><addsrcrecordid>eNptkl1rFDEUhgdRbKm98QdIwBsRZk0mM5PMlWxLtYUFQRQvw9l8dE_JJm0ys7r_xp9qhtZ-iMlFwpvnvIdzcqrqNaMLzgf6IUysbxjvhHxWHTZUNHXft_z5o_tBdZzzFZ2XoKLnL6sDPnRsaBk9rH5fRIPBkhOMsAP0sEaP455AMLOmN3aLGjw5c87qMZPoyEmCnItIorcJtAWyg7QgGdbW-1lfLeZQF9OIDq0hP3HcEFmf702Kv_a1qDGaWHf1zYQh-pI9T97FgJosNRqCgfzAPEIiX2HMr6oXDny2x3fnUfX909m30_N69eXzxelyVWveiLGWTHS054MzhgIMQvaDFhaEbAetS4eMlVQAs5q5ogAbmrY1sDa60x0Yy_hR9fHW93pab63RNowJvLpOuIW0VxFQPX0JuFGXcacY61oxDLPDuzuHFG8mm0e1xaxLTyDYOGXFWSNFy9uuLejbf9CrOKVQ6pupnnJWynmgLsFbhcHFkljPpmopS9aGSioLtfgPVbaZvy4G67DoTwLe3wboFHNO1t0XyaiaZ0o9zFSB3zxuyz36d4L4H42Txzo</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3126031175</pqid></control><display><type>article</type><title>Iodine Bioavailability and Biochemical Effects of Brassica oleracea var. sabellica L. Biofortified with 8-Hydroxy-7-iodo-5-quinolinesulfonic Acid in Wistar Rats</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central Open Access</source><source>MDPI - Multidisciplinary Digital Publishing Institute</source><source>PubMed Central</source><creator>Krzemińska, Joanna ; Piątkowska, Ewa ; Kopeć, Aneta ; Smoleń, Sylwester ; Leszczyńska, Teresa ; Koronowicz, Aneta</creator><creatorcontrib>Krzemińska, Joanna ; Piątkowska, Ewa ; Kopeć, Aneta ; Smoleń, Sylwester ; Leszczyńska, Teresa ; Koronowicz, Aneta</creatorcontrib><description>Iodine is one of the essential trace elements for human life. The main objective of the biofortification of plants with iodine is to obtain food with a higher content of this element compared to conventional food. Biofortification of plants with iodine can increase the intake of this trace element by different populations. In addition, it may reduce the risk of iodine deficiency diseases.
The aim of the study was to investigate the effect of kale biofortified with 8-hydroxy-7-iodo-5-quinolinesulfonic acid (8-OH-7-I-5QSA) on iodine bioavailability and biochemical effects in Wistar rats.
Kale biofortified with (8-OH-7-I-5QSA) was tested for iodine levels in urine, feces, and selected tissues using the ICP-MS/MS technique. The feeding experiment was designed to investigate potential changes in selected thyroid-regulated biochemical parameters in blood serum of Wistar rats.
The dietary intake of Wistar rats fed kale biofortified with (8-OH-7-I-5QSA) from both the "Oldenbor F
" and "Redbor F
" cultivars for 8 weeks resulted in significantly (
≤ 0.05) higher iodine concentrations in the urine and kidneys of rats, which proves iodine bioavailability. Rats' diets with "Oldenbor F
" and "Redbor F
" kale non- and -biofortified with 8-OH-7-I-5QSA had a significantly (
≤ 0.05) lower or a tendency for lower concentration of TSH, triglyceride, total and direct bilirubin, TBARs, uric acid, aspartate aminotransferase (AST) and alanine aminotransferase (ALT) concentrations in serum. Dietary intake of "Oldenbor F
" and "Redbor F
" kale biofortified with 8-OH-7-I-5QSA significantly (
≤ 0.05) increased the total antioxidant status (TAS).
Our study confirms that kale biofortified with iodine in organic form iodoquinoline 8-OH-7-I-5QSA is bioavailable and well absorbed by the Wistar rat and has a positive effect on selected biochemical parameters. The results obtained in this study may be highly predictive for further studies in humans.</description><identifier>ISSN: 2072-6643</identifier><identifier>EISSN: 2072-6643</identifier><identifier>DOI: 10.3390/nu16213578</identifier><identifier>PMID: 39519410</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Animals ; Bilirubin ; Bioavailability ; Biofortification ; Biological Availability ; Biological products ; Brassica - chemistry ; Cancer ; Crop diseases ; Diet ; Dietary minerals ; Experiments ; Food, Fortified ; Genetically altered foods ; Iodine ; Iodine - pharmacokinetics ; Iodine - urine ; Kale ; Laboratories ; Male ; Nutrients ; Quinolines - pharmacokinetics ; Rats ; Rats, Wistar ; Thyroid gland ; Vegetables</subject><ispartof>Nutrients, 2024-10, Vol.16 (21), p.3578</ispartof><rights>COPYRIGHT 2024 MDPI AG</rights><rights>2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2024 by the authors. 2024</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c327t-81750639fdd0aa97869c7ea7849cc162de807a1ec1f49ca19244dabdc5c5ade13</cites><orcidid>0000-0002-2170-2760 ; 0000-0001-8093-3801 ; 0000-0001-6865-6717 ; 0000-0002-9633-945X ; 0000-0002-1653-2867</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11547991/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11547991/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39519410$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Krzemińska, Joanna</creatorcontrib><creatorcontrib>Piątkowska, Ewa</creatorcontrib><creatorcontrib>Kopeć, Aneta</creatorcontrib><creatorcontrib>Smoleń, Sylwester</creatorcontrib><creatorcontrib>Leszczyńska, Teresa</creatorcontrib><creatorcontrib>Koronowicz, Aneta</creatorcontrib><title>Iodine Bioavailability and Biochemical Effects of Brassica oleracea var. sabellica L. Biofortified with 8-Hydroxy-7-iodo-5-quinolinesulfonic Acid in Wistar Rats</title><title>Nutrients</title><addtitle>Nutrients</addtitle><description>Iodine is one of the essential trace elements for human life. The main objective of the biofortification of plants with iodine is to obtain food with a higher content of this element compared to conventional food. Biofortification of plants with iodine can increase the intake of this trace element by different populations. In addition, it may reduce the risk of iodine deficiency diseases.
The aim of the study was to investigate the effect of kale biofortified with 8-hydroxy-7-iodo-5-quinolinesulfonic acid (8-OH-7-I-5QSA) on iodine bioavailability and biochemical effects in Wistar rats.
Kale biofortified with (8-OH-7-I-5QSA) was tested for iodine levels in urine, feces, and selected tissues using the ICP-MS/MS technique. The feeding experiment was designed to investigate potential changes in selected thyroid-regulated biochemical parameters in blood serum of Wistar rats.
The dietary intake of Wistar rats fed kale biofortified with (8-OH-7-I-5QSA) from both the "Oldenbor F
" and "Redbor F
" cultivars for 8 weeks resulted in significantly (
≤ 0.05) higher iodine concentrations in the urine and kidneys of rats, which proves iodine bioavailability. Rats' diets with "Oldenbor F
" and "Redbor F
" kale non- and -biofortified with 8-OH-7-I-5QSA had a significantly (
≤ 0.05) lower or a tendency for lower concentration of TSH, triglyceride, total and direct bilirubin, TBARs, uric acid, aspartate aminotransferase (AST) and alanine aminotransferase (ALT) concentrations in serum. Dietary intake of "Oldenbor F
" and "Redbor F
" kale biofortified with 8-OH-7-I-5QSA significantly (
≤ 0.05) increased the total antioxidant status (TAS).
Our study confirms that kale biofortified with iodine in organic form iodoquinoline 8-OH-7-I-5QSA is bioavailable and well absorbed by the Wistar rat and has a positive effect on selected biochemical parameters. The results obtained in this study may be highly predictive for further studies in humans.</description><subject>Animals</subject><subject>Bilirubin</subject><subject>Bioavailability</subject><subject>Biofortification</subject><subject>Biological Availability</subject><subject>Biological products</subject><subject>Brassica - chemistry</subject><subject>Cancer</subject><subject>Crop diseases</subject><subject>Diet</subject><subject>Dietary minerals</subject><subject>Experiments</subject><subject>Food, Fortified</subject><subject>Genetically altered foods</subject><subject>Iodine</subject><subject>Iodine - pharmacokinetics</subject><subject>Iodine - urine</subject><subject>Kale</subject><subject>Laboratories</subject><subject>Male</subject><subject>Nutrients</subject><subject>Quinolines - pharmacokinetics</subject><subject>Rats</subject><subject>Rats, Wistar</subject><subject>Thyroid gland</subject><subject>Vegetables</subject><issn>2072-6643</issn><issn>2072-6643</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNptkl1rFDEUhgdRbKm98QdIwBsRZk0mM5PMlWxLtYUFQRQvw9l8dE_JJm0ys7r_xp9qhtZ-iMlFwpvnvIdzcqrqNaMLzgf6IUysbxjvhHxWHTZUNHXft_z5o_tBdZzzFZ2XoKLnL6sDPnRsaBk9rH5fRIPBkhOMsAP0sEaP455AMLOmN3aLGjw5c87qMZPoyEmCnItIorcJtAWyg7QgGdbW-1lfLeZQF9OIDq0hP3HcEFmf702Kv_a1qDGaWHf1zYQh-pI9T97FgJosNRqCgfzAPEIiX2HMr6oXDny2x3fnUfX909m30_N69eXzxelyVWveiLGWTHS054MzhgIMQvaDFhaEbAetS4eMlVQAs5q5ogAbmrY1sDa60x0Yy_hR9fHW93pab63RNowJvLpOuIW0VxFQPX0JuFGXcacY61oxDLPDuzuHFG8mm0e1xaxLTyDYOGXFWSNFy9uuLejbf9CrOKVQ6pupnnJWynmgLsFbhcHFkljPpmopS9aGSioLtfgPVbaZvy4G67DoTwLe3wboFHNO1t0XyaiaZ0o9zFSB3zxuyz36d4L4H42Txzo</recordid><startdate>20241022</startdate><enddate>20241022</enddate><creator>Krzemińska, Joanna</creator><creator>Piątkowska, Ewa</creator><creator>Kopeć, Aneta</creator><creator>Smoleń, Sylwester</creator><creator>Leszczyńska, Teresa</creator><creator>Koronowicz, Aneta</creator><general>MDPI AG</general><general>MDPI</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TS</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-2170-2760</orcidid><orcidid>https://orcid.org/0000-0001-8093-3801</orcidid><orcidid>https://orcid.org/0000-0001-6865-6717</orcidid><orcidid>https://orcid.org/0000-0002-9633-945X</orcidid><orcidid>https://orcid.org/0000-0002-1653-2867</orcidid></search><sort><creationdate>20241022</creationdate><title>Iodine Bioavailability and Biochemical Effects of Brassica oleracea var. sabellica L. Biofortified with 8-Hydroxy-7-iodo-5-quinolinesulfonic Acid in Wistar Rats</title><author>Krzemińska, Joanna ; Piątkowska, Ewa ; Kopeć, Aneta ; Smoleń, Sylwester ; Leszczyńska, Teresa ; Koronowicz, Aneta</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c327t-81750639fdd0aa97869c7ea7849cc162de807a1ec1f49ca19244dabdc5c5ade13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Animals</topic><topic>Bilirubin</topic><topic>Bioavailability</topic><topic>Biofortification</topic><topic>Biological Availability</topic><topic>Biological products</topic><topic>Brassica - chemistry</topic><topic>Cancer</topic><topic>Crop diseases</topic><topic>Diet</topic><topic>Dietary minerals</topic><topic>Experiments</topic><topic>Food, Fortified</topic><topic>Genetically altered foods</topic><topic>Iodine</topic><topic>Iodine - pharmacokinetics</topic><topic>Iodine - urine</topic><topic>Kale</topic><topic>Laboratories</topic><topic>Male</topic><topic>Nutrients</topic><topic>Quinolines - pharmacokinetics</topic><topic>Rats</topic><topic>Rats, Wistar</topic><topic>Thyroid gland</topic><topic>Vegetables</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Krzemińska, Joanna</creatorcontrib><creatorcontrib>Piątkowska, Ewa</creatorcontrib><creatorcontrib>Kopeć, Aneta</creatorcontrib><creatorcontrib>Smoleń, Sylwester</creatorcontrib><creatorcontrib>Leszczyńska, Teresa</creatorcontrib><creatorcontrib>Koronowicz, Aneta</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Physical Education Index</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Nutrients</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Krzemińska, Joanna</au><au>Piątkowska, Ewa</au><au>Kopeć, Aneta</au><au>Smoleń, Sylwester</au><au>Leszczyńska, Teresa</au><au>Koronowicz, Aneta</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Iodine Bioavailability and Biochemical Effects of Brassica oleracea var. sabellica L. Biofortified with 8-Hydroxy-7-iodo-5-quinolinesulfonic Acid in Wistar Rats</atitle><jtitle>Nutrients</jtitle><addtitle>Nutrients</addtitle><date>2024-10-22</date><risdate>2024</risdate><volume>16</volume><issue>21</issue><spage>3578</spage><pages>3578-</pages><issn>2072-6643</issn><eissn>2072-6643</eissn><abstract>Iodine is one of the essential trace elements for human life. The main objective of the biofortification of plants with iodine is to obtain food with a higher content of this element compared to conventional food. Biofortification of plants with iodine can increase the intake of this trace element by different populations. In addition, it may reduce the risk of iodine deficiency diseases.
The aim of the study was to investigate the effect of kale biofortified with 8-hydroxy-7-iodo-5-quinolinesulfonic acid (8-OH-7-I-5QSA) on iodine bioavailability and biochemical effects in Wistar rats.
Kale biofortified with (8-OH-7-I-5QSA) was tested for iodine levels in urine, feces, and selected tissues using the ICP-MS/MS technique. The feeding experiment was designed to investigate potential changes in selected thyroid-regulated biochemical parameters in blood serum of Wistar rats.
The dietary intake of Wistar rats fed kale biofortified with (8-OH-7-I-5QSA) from both the "Oldenbor F
" and "Redbor F
" cultivars for 8 weeks resulted in significantly (
≤ 0.05) higher iodine concentrations in the urine and kidneys of rats, which proves iodine bioavailability. Rats' diets with "Oldenbor F
" and "Redbor F
" kale non- and -biofortified with 8-OH-7-I-5QSA had a significantly (
≤ 0.05) lower or a tendency for lower concentration of TSH, triglyceride, total and direct bilirubin, TBARs, uric acid, aspartate aminotransferase (AST) and alanine aminotransferase (ALT) concentrations in serum. Dietary intake of "Oldenbor F
" and "Redbor F
" kale biofortified with 8-OH-7-I-5QSA significantly (
≤ 0.05) increased the total antioxidant status (TAS).
Our study confirms that kale biofortified with iodine in organic form iodoquinoline 8-OH-7-I-5QSA is bioavailable and well absorbed by the Wistar rat and has a positive effect on selected biochemical parameters. The results obtained in this study may be highly predictive for further studies in humans.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>39519410</pmid><doi>10.3390/nu16213578</doi><orcidid>https://orcid.org/0000-0002-2170-2760</orcidid><orcidid>https://orcid.org/0000-0001-8093-3801</orcidid><orcidid>https://orcid.org/0000-0001-6865-6717</orcidid><orcidid>https://orcid.org/0000-0002-9633-945X</orcidid><orcidid>https://orcid.org/0000-0002-1653-2867</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2072-6643 |
| ispartof | Nutrients, 2024-10, Vol.16 (21), p.3578 |
| issn | 2072-6643 2072-6643 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11547991 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central Open Access; MDPI - Multidisciplinary Digital Publishing Institute; PubMed Central |
| subjects | Animals Bilirubin Bioavailability Biofortification Biological Availability Biological products Brassica - chemistry Cancer Crop diseases Diet Dietary minerals Experiments Food, Fortified Genetically altered foods Iodine Iodine - pharmacokinetics Iodine - urine Kale Laboratories Male Nutrients Quinolines - pharmacokinetics Rats Rats, Wistar Thyroid gland Vegetables |
| title | Iodine Bioavailability and Biochemical Effects of Brassica oleracea var. sabellica L. Biofortified with 8-Hydroxy-7-iodo-5-quinolinesulfonic Acid in Wistar Rats |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-05T12%3A27%3A08IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Iodine%20Bioavailability%20and%20Biochemical%20Effects%20of%20Brassica%20oleracea%20var.%20sabellica%20L.%20Biofortified%20with%208-Hydroxy-7-iodo-5-quinolinesulfonic%20Acid%20in%20Wistar%20Rats&rft.jtitle=Nutrients&rft.au=Krzemi%C5%84ska,%20Joanna&rft.date=2024-10-22&rft.volume=16&rft.issue=21&rft.spage=3578&rft.pages=3578-&rft.issn=2072-6643&rft.eissn=2072-6643&rft_id=info:doi/10.3390/nu16213578&rft_dat=%3Cgale_pubme%3EA815420808%3C/gale_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=3126031175&rft_id=info:pmid/39519410&rft_galeid=A815420808&rfr_iscdi=true |