Vitex agnus castus Extract Ze 440: Diterpene and Triterpene's Interactions with Dopamine D2 Receptor

Pre-clinical studies suggest that extracts prepared from the fruits of (VAC) interact with dopamine D2 receptors, leading to reduced prolactin secretion. In previous experiments, dopaminergic activity was mostly evaluated using radioligand binding assays or via the inhibition of prolactin release fr...

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Veröffentlicht in:	International journal of molecular sciences 2024-11, Vol.25 (21), p.11456
Hauptverfasser:	Reinhardt, Jakob K, Schertler, Lukas, Bussmann, Hendrik, Sellner, Manuel, Smiesko, Martin, Boonen, Georg, Potterat, Olivier, Hamburger, Matthias, Butterweck, Veronika
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Animals Breastfeeding & lactation Care and treatment Chemical properties CHO Cells Cricetulus Development and progression Diterpenes Diterpenes - chemistry Diterpenes - pharmacology Dopamine Dopamine receptors Females Health aspects Humans Identification and classification Ligands Menstruation Molecular Docking Simulation Physiological aspects Phytochemicals Plant Extracts - chemistry Plant Extracts - pharmacology PMS Premenstrual syndrome Receptors, Dopamine D2 - metabolism Triterpenes - chemistry Triterpenes - pharmacology Vitex Vitex - chemistry
Online-Zugang:	Volltext
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