SNHG15 Mediates MTSS1 Gene Expression via Interacting with the Gene Promoter and Regulating Transcription Pausing

Metastasis suppressor 1 (MTSS1) has been reported to play important roles in suppressing cancer progression. In this study, we investigated the underlying mechanism that regulates MTSS1 expression. We showed that in breast cancer cells, lncRNA-SNHG15-induced cell invasion and proliferation was accom...

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Veröffentlicht in:	International journal of molecular sciences 2024-11, Vol.25 (21), p.11565
Hauptverfasser:	Zhou, Yanchun, Chen, Shaoying, Chen, Weibin, Wu, Jundong, Gu, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast cancer Breast Neoplasms - genetics Breast Neoplasms - metabolism Breast Neoplasms - pathology Cell growth Cell Line, Tumor Cell Proliferation - genetics DEAD-box RNA Helicases - genetics DEAD-box RNA Helicases - metabolism Development and progression DNA methylation Ethylenediaminetetraacetic acid Female Gene expression Gene Expression Regulation, Neoplastic Genes Genetic aspects Genetic transcription Humans Mediation Messenger RNA Metastasis Microfilament Proteins - genetics Microfilament Proteins - metabolism Neoplasm Proteins - genetics Neoplasm Proteins - metabolism Promoter Regions, Genetic Promoters (Genetics) Proteins RNA polymerase RNA, Long Noncoding - genetics RNA, Long Noncoding - metabolism Scientific imaging Transcription, Genetic Tumors
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