Abundant amounts of diadenosine 5',5"'-P1,P4-tetraphosphate are present and releasable, but metabolically inactive, in human platelets

Diadenosine 5',5"'-P1,P4-tetraphosphate (Ap4A) may be formed in the back reaction of the amino acid-activation reaction [Zamecnik, Stephenson, Janeway & Randerath (1966) Biochem. Biophys. Res. Commun. 24, 91-98]. On the basis of a number of observations of the properties of Ap4A i...

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Veröffentlicht in:	Biochemical journal 1982-12, Vol.208 (3), p.737-742
Hauptverfasser:	Flodgaard, H, Klenow, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenine Nucleotides - blood Adenosine Triphosphate - blood Blood Platelets - drug effects Blood Platelets - metabolism Chromatography, High Pressure Liquid Dinucleoside Phosphates Humans In Vitro Techniques Phosphodiesterase I Phosphoric Diester Hydrolases - pharmacology Platelet Aggregation - drug effects Ribonucleotides - blood Thrombin - pharmacology
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