Synthesis, in silico and bio-evaluation studies of new isothiocyanate derivatives with respect to COX inhibition and H2S release profiles

The development of H2S-donating derivatives of non-steroidal anti-inflammatory drugs (NSAIDs) is considered important to reduce or overcome their gastrointestinal side effects. Sulforaphane, one of the most extensively studied isothiocyanates (ITCs), effectively releases H2S at a slow rate. Thus, we...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	RSC medicinal chemistry 2024-10
Hauptverfasser:	Yilmaz, Yakup Berkay, Güngör, Tuğba, Dönmez, Serhat, Atalay, Hazal Nazlıcan, Siyah, Pınar, Durdağı, Serdar, Ay, Mehmet, Boyunegmez Tumer, Tugba
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!