Isolated Pancreatic Metastasis in a Patient With Orbital Rhabdomyosarcoma: A Report of a Rare Case
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children and adolescents and its occurrence in adults is extremely rare. There are three major subtypes of RMS of which alveolar RMS (ARMS) has the worst prognosis and tends to metastasize to unusual locations such as the pancreas. We...
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| Veröffentlicht in: | Curēus (Palo Alto, CA) CA), 2024-10, Vol.16 (10), p.e70770 |
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| creator | Idrees, Rana Bilal Malik, Mariam Mustanser, Ahmed Sarwar, Taimoor Kousar, Farzana Chaudhary, Muhammad Hamid |
| description | Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children and adolescents and its occurrence in adults is extremely rare. There are three major subtypes of RMS of which alveolar RMS (ARMS) has the worst prognosis and tends to metastasize to unusual locations such as the pancreas. We present a case of a 19-year-old male with a rapidly enlarging right orbital mass, the imaging of which revealed it to be an infiltrative lesion with extension into the nasal cavity, ethmoid sinuses, and intracranial involvement. Histopathology confirmed the diagnosis of ARMS. A staging CT scan showed an enlarged and hypoenhancing pancreas; the histopathology test confirmed ARMS metastasis. It is important to consider pancreatic involvement in patients with ARMS, as it may be misinterpreted with other pathologies such as pancreatitis and pancreatic lymphoma. Metastasis to the pancreas can significantly alter the clinical approach and staging, underscoring the need for accurate diagnosis and staging in these patients. |
| doi_str_mv | 10.7759/cureus.70770 |
| format | Article |
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There are three major subtypes of RMS of which alveolar RMS (ARMS) has the worst prognosis and tends to metastasize to unusual locations such as the pancreas. We present a case of a 19-year-old male with a rapidly enlarging right orbital mass, the imaging of which revealed it to be an infiltrative lesion with extension into the nasal cavity, ethmoid sinuses, and intracranial involvement. Histopathology confirmed the diagnosis of ARMS. A staging CT scan showed an enlarged and hypoenhancing pancreas; the histopathology test confirmed ARMS metastasis. It is important to consider pancreatic involvement in patients with ARMS, as it may be misinterpreted with other pathologies such as pancreatitis and pancreatic lymphoma. Metastasis to the pancreas can significantly alter the clinical approach and staging, underscoring the need for accurate diagnosis and staging in these patients.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.70770</identifier><identifier>PMID: 39493131</identifier><language>eng</language><publisher>United States: Cureus Inc</publisher><subject>Abdomen ; Adults ; Biopsy ; Cancer ; Histopathology ; Hospitals ; Lymphoma ; Medical prognosis ; Metastasis ; Nuclear medicine ; Oncology ; Pancreas ; Patients ; Radiation therapy ; Radiology ; Sarcoma</subject><ispartof>Curēus (Palo Alto, CA), 2024-10, Vol.16 (10), p.e70770</ispartof><rights>Copyright © 2024, Idrees et al.</rights><rights>Copyright © 2024, Idrees et al. This work is published under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2024, Idrees et al. 2024 Idrees et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c2150-c0d2b88b0acf282a31b47455684593936c87743d481ab35b52e6cedbe89c99f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11531306/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11531306/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39493131$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Idrees, Rana Bilal</creatorcontrib><creatorcontrib>Malik, Mariam</creatorcontrib><creatorcontrib>Mustanser, Ahmed</creatorcontrib><creatorcontrib>Sarwar, Taimoor</creatorcontrib><creatorcontrib>Kousar, Farzana</creatorcontrib><creatorcontrib>Chaudhary, Muhammad Hamid</creatorcontrib><title>Isolated Pancreatic Metastasis in a Patient With Orbital Rhabdomyosarcoma: A Report of a Rare Case</title><title>Curēus (Palo Alto, CA)</title><addtitle>Cureus</addtitle><description>Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children and adolescents and its occurrence in adults is extremely rare. 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Metastasis to the pancreas can significantly alter the clinical approach and staging, underscoring the need for accurate diagnosis and staging in these patients.</description><subject>Abdomen</subject><subject>Adults</subject><subject>Biopsy</subject><subject>Cancer</subject><subject>Histopathology</subject><subject>Hospitals</subject><subject>Lymphoma</subject><subject>Medical prognosis</subject><subject>Metastasis</subject><subject>Nuclear medicine</subject><subject>Oncology</subject><subject>Pancreas</subject><subject>Patients</subject><subject>Radiation therapy</subject><subject>Radiology</subject><subject>Sarcoma</subject><issn>2168-8184</issn><issn>2168-8184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpdkd1LHDEUxUNpqbL1rc8l4EsfXJvPScYXkcVawWJZhD6Gm0zGjcxM1iQj-N837apoIXAD93cP596D0GdKjpWS7Tc3Jz_nY0WUIu_QPqONXmqqxftX_z10kPMdIYQSxYgiH9Eeb0XLKaf7yF7mOEDxHf4Fk0seSnD4py-Q6wsZhwlDbZXgp4J_h7LB18mGAgNeb8B2cXyMGZKLI5zgM7z225gKjn0dWkPyeAXZf0IfehiyP3iqC3Tz_fxm9WN5dX1xuTq7WjpGJVk60jGrtSXgeqYZcGqFElI2WsiWt7xxWinBO6EpWC6tZL5xvrNet65te75ApzvZ7WxH37lqOMFgtimMkB5NhGDedqawMbfxwVAq6y1IUxW-PimkeD_7XMwYsvPDAJOPczacMq5J00hS0cP_0Ls4p6muVykuhGxYtbxARzvKpZhz8v2LG0rM3_zMLj_zL7-Kf3m9wQv8nBb_A1Uslp4</recordid><startdate>20241003</startdate><enddate>20241003</enddate><creator>Idrees, Rana Bilal</creator><creator>Malik, Mariam</creator><creator>Mustanser, Ahmed</creator><creator>Sarwar, Taimoor</creator><creator>Kousar, Farzana</creator><creator>Chaudhary, Muhammad Hamid</creator><general>Cureus Inc</general><general>Cureus</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20241003</creationdate><title>Isolated Pancreatic Metastasis in a Patient With Orbital Rhabdomyosarcoma: A Report of a Rare Case</title><author>Idrees, Rana Bilal ; 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There are three major subtypes of RMS of which alveolar RMS (ARMS) has the worst prognosis and tends to metastasize to unusual locations such as the pancreas. We present a case of a 19-year-old male with a rapidly enlarging right orbital mass, the imaging of which revealed it to be an infiltrative lesion with extension into the nasal cavity, ethmoid sinuses, and intracranial involvement. Histopathology confirmed the diagnosis of ARMS. A staging CT scan showed an enlarged and hypoenhancing pancreas; the histopathology test confirmed ARMS metastasis. It is important to consider pancreatic involvement in patients with ARMS, as it may be misinterpreted with other pathologies such as pancreatitis and pancreatic lymphoma. Metastasis to the pancreas can significantly alter the clinical approach and staging, underscoring the need for accurate diagnosis and staging in these patients.</abstract><cop>United States</cop><pub>Cureus Inc</pub><pmid>39493131</pmid><doi>10.7759/cureus.70770</doi><oa>free_for_read</oa></addata></record> |
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| source | PubMed Central Open Access; PubMed Central |
| subjects | Abdomen Adults Biopsy Cancer Histopathology Hospitals Lymphoma Medical prognosis Metastasis Nuclear medicine Oncology Pancreas Patients Radiation therapy Radiology Sarcoma |
| title | Isolated Pancreatic Metastasis in a Patient With Orbital Rhabdomyosarcoma: A Report of a Rare Case |
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