Impact of Different Packaging Configurations on A Topical Cream Product

Purpose The objective of this study was to investigate whether different dispensing processes can alter the physicochemical and structural (Q3) attributes of a topical cream product, and potentially alter its performance. Methods Acyclovir cream, 5% (Zovirax®) is sold in the UK and other countries i...

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Veröffentlicht in:	Pharmaceutical research 2024-10, Vol.41 (10), p.2043-2056
Hauptverfasser:	Mohammed, Yousuf H., Namjoshi, S. N., Telaprolu, K. C., Jung, N., Shewan, H. M., Stokes, J. R., Benson, H. A. E., Grice, J. E., Raney, S. G., Rantou, E., Windbergs, Maike, Roberts, Michael S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acyclovir Acyclovir - administration & dosage Acyclovir - chemistry Acyclovir - pharmacokinetics Administration, Cutaneous Antiviral Agents - administration & dosage Antiviral Agents - chemistry Antiviral Agents - pharmacokinetics Bioavailability Biochemistry Biomedical and Life Sciences Biomedical Engineering and Bioengineering Biomedicine Dimethylpolysiloxane Drug Packaging Epidermis Epidermis - metabolism Generic products Humans Light microscopy Medical Law Metamorphosis Microscopy Original Original Research Article Patient compliance Pharmacology/Toxicology Pharmacy Polydimethylsiloxane Rheology Scanning electron microscopy Skin Skin Absorption Skin Cream - administration & dosage Skin Cream - chemistry Skin tests
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