Machine Learning Reveals the Diversity of Human 3D Chromatin Contact Patterns

Abstract Understanding variation in chromatin contact patterns across diverse humans is critical for interpreting noncoding variants and their effects on gene expression and phenotypes. However, experimental determination of chromatin contact patterns across large samples is prohibitively expensive....

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Veröffentlicht in:	Molecular biology and evolution 2024-10, Vol.41 (10)
Hauptverfasser:	Gilbertson, Erin N, Brand, Colin M, McArthur, Evonne, Rinker, David C, Kuang, Shuzhen, Pollard, Katherine S, Capra, John A
Format:	Artikel
Sprache:	eng
Schlagworte:	Chromatin - genetics Discoveries Genetic Variation Genome, Human Humans Machine Learning
Online-Zugang:	Volltext
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