Bone sialoprotein facilitates anoikis resistance in lung cancer by inhibiting miR‐150‐5p expression

Metastatic lung cancer is a highly prevalent cancer with a very low chance of long‐term survival. Metastasis at secondary sites requires that cancer cells develop anoikis resistance to survive during circulation. High levels of bone sialoprotein (BSP), a member of the small integrin‐binding ligand N...

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Veröffentlicht in:	Journal of cellular and molecular medicine 2024-10, Vol.28 (20), p.e70155-n/a
Hauptverfasser:	Thuong, Le Huynh Hoai, Huang, Chang‐Lun, Fong, Yi‐Chin, Liu, Chun‐Lin, Guo, Jeng‐Hung, Wu, Chih‐Ying, Liu, Po‐I, Tang, Chih‐Hsin
Format:	Artikel
Sprache:	eng
Schlagworte:	A549 Cells Animals Anoikis Anoikis - genetics anoikis resistance Antibodies Apoptosis Bone cancer Bone sialoprotein BSP Cadherins - genetics Cadherins - metabolism Cancer therapies Cell cycle Cell Line, Tumor Cell survival Datasets Epithelial-Mesenchymal Transition - genetics Gene expression Gene Expression Regulation, Neoplastic Glycoproteins Humans Integrin-Binding Sialoprotein - genetics Integrin-Binding Sialoprotein - metabolism Long bone Lung cancer Lung Neoplasms - genetics Lung Neoplasms - metabolism Lung Neoplasms - pathology MAP Kinase Signaling System Medical research Metastases Metastasis Mice Mice, Nude MicroRNAs MicroRNAs - genetics MicroRNAs - metabolism miR‐150‐5p Original Plasmids Proteins Signal transduction Vimentin Vimentin - genetics Vimentin - metabolism
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