Breaking boundaries in diabetic nephropathy treatment: design and synthesis of novel steroidal SGLT2 inhibitors

The activity of sodium glucose co-transporter 2 (SGLT2) has always been an important parameter influencing chronic kidney disease in type-2 diabetic patients. Herein, we have meticulously designed, synthesized, and evaluated several novel steroidal pyrimidine molecules that possess the capability to...

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Veröffentlicht in:	RSC medicinal chemistry 2024-10
Hauptverfasser:	Nongthombam, Geetmani Singh, Ahmed, Semim Akhtar, Saikia, Kangkon, Gogoi, Sanjib, Borah, Jagat Chandra
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry
Online-Zugang:	Volltext
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