Quantal Ca2+ mobilization stimulated by inositol 1,4,5-trisphosphate in permeabilized hepatocytes

In several cell types, including hepatocytes, submaximal concentrations of Ins(1,4,5)P3 stimulate an initial rapid mobilization of intracellular Ca2+ stores that is followed by either no further Ca2+ release or very much slower release. Further additions of Ins(1,4,5)P3 then evoke further Ca2+ mobil...

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Veröffentlicht in:	Biochemical journal 1991-09, Vol.278 ( Pt 3) (3), p.705-708
Hauptverfasser:	Oldershaw, K A, Nunn, D L, Taylor, C W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcium - metabolism Calcium Radioisotopes Cell Membrane Permeability Inositol 1,4,5-Trisphosphate - pharmacology Kinetics Liver - drug effects Liver - metabolism Male Rats Rats, Inbred Strains
Online-Zugang:	Volltext
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