Gene therapy for chronic pain management

Despite significant advances in identifying molecular targets for chronic pain over the past two decades, many remain difficult to target with traditional methods. Gene therapies such as antisense oligonucleotides (ASOs), RNA interference (RNAi), CRISPR, and virus-based delivery systems have played...

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Veröffentlicht in:	Cell reports. Medicine 2024-10, Vol.5 (10), p.101756, Article 101756
Hauptverfasser:	Li, Yi-ze, Ji, Ru-Rong
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chronic Pain - genetics Chronic Pain - therapy Genetic Therapy - methods Humans Oligonucleotides, Antisense - genetics Oligonucleotides, Antisense - therapeutic use Optogenetics - methods Pain Management - methods Review RNA, Small Interfering - genetics Sensory Receptor Cells - metabolism
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