The Potential Role of Cannabidiol in Cosmetic Dermatology: A Literature Review
Cannabidiol (CBD) is a non-psychotropic cannabinoid with multiple pharmacological properties. Cannabidiol has attracted growing attention in the cosmetic industry, with an increasing number of CBD-containing skincare products on the market in recent years. The aim of this review is to evaluate the c...
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| Veröffentlicht in: | American journal of clinical dermatology 2024-11, Vol.25 (6), p.951-966 |
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| container_title | American journal of clinical dermatology |
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| creator | Kuzumi, Ai Yoshizaki-Ogawa, Asako Fukasawa, Takemichi Sato, Shinichi Yoshizaki, Ayumi |
| description | Cannabidiol (CBD) is a non-psychotropic cannabinoid with multiple pharmacological properties. Cannabidiol has attracted growing attention in the cosmetic industry, with an increasing number of CBD-containing skincare products on the market in recent years. The aim of this review is to evaluate the current evidence on the use of CBD for cosmetic purposes. Following an overview of CBD and the endocannabinoid system in the skin, we summarize pre-clinical and clinical studies that address the potential of CBD in cosmetic dermatology. Available in vitro and in vivo evidence suggests that CBD has anti-oxidant, anti-inflammatory, moisturizing, anti-acne, wound-healing, and anti-aging properties. However, only a few clinical studies have been conducted on the use of CBD in the skin. In addition, there is a critical need to develop an efficient drug-delivery system for topical/transdermal application of CBD. Further research, including clinical and pharmacokinetic studies, are needed to fully evaluate the role of CBD in cosmetic dermatology. |
| doi_str_mv | 10.1007/s40257-024-00891-y |
| format | Article |
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Cannabidiol has attracted growing attention in the cosmetic industry, with an increasing number of CBD-containing skincare products on the market in recent years. The aim of this review is to evaluate the current evidence on the use of CBD for cosmetic purposes. Following an overview of CBD and the endocannabinoid system in the skin, we summarize pre-clinical and clinical studies that address the potential of CBD in cosmetic dermatology. Available in vitro and in vivo evidence suggests that CBD has anti-oxidant, anti-inflammatory, moisturizing, anti-acne, wound-healing, and anti-aging properties. However, only a few clinical studies have been conducted on the use of CBD in the skin. In addition, there is a critical need to develop an efficient drug-delivery system for topical/transdermal application of CBD. Further research, including clinical and pharmacokinetic studies, are needed to fully evaluate the role of CBD in cosmetic dermatology.</description><identifier>ISSN: 1175-0561</identifier><identifier>ISSN: 1179-1888</identifier><identifier>EISSN: 1179-1888</identifier><identifier>DOI: 10.1007/s40257-024-00891-y</identifier><identifier>PMID: 39369127</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject><![CDATA[Administration, Cutaneous ; Animals ; Anti-Inflammatory Agents - administration & dosage ; Anti-Inflammatory Agents - pharmacology ; Antioxidants ; Antioxidants - administration & dosage ; Antioxidants - pharmacology ; Binding sites ; Cannabidiol ; Cannabidiol - administration & dosage ; Cannabidiol - pharmacology ; Cannabidiol - therapeutic use ; Cosmetics - administration & dosage ; Dermatitis ; Dermatologic Agents - administration & dosage ; Dermatologic Agents - pharmacology ; Dermatologic Agents - therapeutic use ; Dermatology ; Dermatology - methods ; Enzymes ; Fatty acids ; Fibroblasts ; Homeostasis ; Humans ; Inflammation ; Medicine ; Medicine & Public Health ; Oxidative stress ; Pharmacology/Toxicology ; Pharmacotherapy ; Proteins ; Review ; Review Article ; Skin ; Skin - drug effects ; Skin - metabolism ; Skin Aging - drug effects ; Tetrahydrocannabinol ; THC ; Transcription factors ; Tumor necrosis factor-TNF ; Wound Healing - drug effects]]></subject><ispartof>American journal of clinical dermatology, 2024-11, Vol.25 (6), p.951-966</ispartof><rights>The Author(s) 2024</rights><rights>2024. 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Cannabidiol has attracted growing attention in the cosmetic industry, with an increasing number of CBD-containing skincare products on the market in recent years. The aim of this review is to evaluate the current evidence on the use of CBD for cosmetic purposes. Following an overview of CBD and the endocannabinoid system in the skin, we summarize pre-clinical and clinical studies that address the potential of CBD in cosmetic dermatology. Available in vitro and in vivo evidence suggests that CBD has anti-oxidant, anti-inflammatory, moisturizing, anti-acne, wound-healing, and anti-aging properties. However, only a few clinical studies have been conducted on the use of CBD in the skin. In addition, there is a critical need to develop an efficient drug-delivery system for topical/transdermal application of CBD. Further research, including clinical and pharmacokinetic studies, are needed to fully evaluate the role of CBD in cosmetic dermatology.</description><subject>Administration, Cutaneous</subject><subject>Animals</subject><subject>Anti-Inflammatory Agents - administration & dosage</subject><subject>Anti-Inflammatory Agents - pharmacology</subject><subject>Antioxidants</subject><subject>Antioxidants - administration & dosage</subject><subject>Antioxidants - pharmacology</subject><subject>Binding sites</subject><subject>Cannabidiol</subject><subject>Cannabidiol - administration & dosage</subject><subject>Cannabidiol - pharmacology</subject><subject>Cannabidiol - therapeutic use</subject><subject>Cosmetics - administration & dosage</subject><subject>Dermatitis</subject><subject>Dermatologic Agents - administration & dosage</subject><subject>Dermatologic Agents - pharmacology</subject><subject>Dermatologic Agents - therapeutic use</subject><subject>Dermatology</subject><subject>Dermatology - methods</subject><subject>Enzymes</subject><subject>Fatty acids</subject><subject>Fibroblasts</subject><subject>Homeostasis</subject><subject>Humans</subject><subject>Inflammation</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Oxidative stress</subject><subject>Pharmacology/Toxicology</subject><subject>Pharmacotherapy</subject><subject>Proteins</subject><subject>Review</subject><subject>Review Article</subject><subject>Skin</subject><subject>Skin - drug effects</subject><subject>Skin - metabolism</subject><subject>Skin Aging - drug effects</subject><subject>Tetrahydrocannabinol</subject><subject>THC</subject><subject>Transcription factors</subject><subject>Tumor necrosis factor-TNF</subject><subject>Wound Healing - drug effects</subject><issn>1175-0561</issn><issn>1179-1888</issn><issn>1179-1888</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>EIF</sourceid><recordid>eNp9kU1P3DAQhq0KVD7aP9ADssSFS4rHjhOnF4QW2iKt2grRs-V1xotRElM7Ae2_x7CUrwOag0eaZ17PzEvIF2BfgbH6MJWMy7pgvCwYUw0Uqw9kG6BuClBKbTzksmCygi2yk9IVYzxH9ZFsiUZUDfB6m_y6uET6J4w4jN509Dx0SIOjMzMMZuFbHzrqBzoLqcfRW3qCsTdj6MJy9Y0e07kfMZpxikjP8cbj7Sey6UyX8PPju0v-fj-9mP0s5r9_nM2O54UVshqLmi0kyEYY7hbKtbUCqaxVUAvRWgeGKSdk0xjZguOtqbhrKmnRudoqCbwUu-RorXs9LXpsbR4_mk5fR9-buNLBeP26MvhLvQw3GkDmqzCWFQ4eFWL4N2Eade-Txa4zA4YpaQEghLo_cEb336BXYYpD3i9TvIRSlBXPFF9TNoaUIrqnaYDpe7_02i-d_dIPfulVbtp7ucdTy3-DMiDWQMqlYYnx-e93ZO8AnlWg6g</recordid><startdate>20241101</startdate><enddate>20241101</enddate><creator>Kuzumi, Ai</creator><creator>Yoshizaki-Ogawa, Asako</creator><creator>Fukasawa, Takemichi</creator><creator>Sato, Shinichi</creator><creator>Yoshizaki, Ayumi</creator><general>Springer International Publishing</general><general>Springer Nature B.V</general><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>4T-</scope><scope>K9.</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-8194-9140</orcidid></search><sort><creationdate>20241101</creationdate><title>The Potential Role of Cannabidiol in Cosmetic Dermatology: A Literature Review</title><author>Kuzumi, Ai ; Yoshizaki-Ogawa, Asako ; Fukasawa, Takemichi ; Sato, Shinichi ; Yoshizaki, Ayumi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c356t-70b51593a2fb8fd78158cc81733dcf1a08f3599a5d1f2da62f965ceff7c851243</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Administration, Cutaneous</topic><topic>Animals</topic><topic>Anti-Inflammatory Agents - administration & dosage</topic><topic>Anti-Inflammatory Agents - pharmacology</topic><topic>Antioxidants</topic><topic>Antioxidants - administration & dosage</topic><topic>Antioxidants - pharmacology</topic><topic>Binding sites</topic><topic>Cannabidiol</topic><topic>Cannabidiol - administration & dosage</topic><topic>Cannabidiol - pharmacology</topic><topic>Cannabidiol - therapeutic use</topic><topic>Cosmetics - administration & dosage</topic><topic>Dermatitis</topic><topic>Dermatologic Agents - administration & dosage</topic><topic>Dermatologic Agents - pharmacology</topic><topic>Dermatologic Agents - therapeutic use</topic><topic>Dermatology</topic><topic>Dermatology - methods</topic><topic>Enzymes</topic><topic>Fatty acids</topic><topic>Fibroblasts</topic><topic>Homeostasis</topic><topic>Humans</topic><topic>Inflammation</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Oxidative stress</topic><topic>Pharmacology/Toxicology</topic><topic>Pharmacotherapy</topic><topic>Proteins</topic><topic>Review</topic><topic>Review Article</topic><topic>Skin</topic><topic>Skin - drug effects</topic><topic>Skin - metabolism</topic><topic>Skin Aging - drug effects</topic><topic>Tetrahydrocannabinol</topic><topic>THC</topic><topic>Transcription factors</topic><topic>Tumor necrosis factor-TNF</topic><topic>Wound Healing - drug effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kuzumi, Ai</creatorcontrib><creatorcontrib>Yoshizaki-Ogawa, Asako</creatorcontrib><creatorcontrib>Fukasawa, Takemichi</creatorcontrib><creatorcontrib>Sato, Shinichi</creatorcontrib><creatorcontrib>Yoshizaki, Ayumi</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Docstoc</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>American journal of clinical dermatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kuzumi, Ai</au><au>Yoshizaki-Ogawa, Asako</au><au>Fukasawa, Takemichi</au><au>Sato, Shinichi</au><au>Yoshizaki, Ayumi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Potential Role of Cannabidiol in Cosmetic Dermatology: A Literature Review</atitle><jtitle>American journal of clinical dermatology</jtitle><stitle>Am J Clin Dermatol</stitle><addtitle>Am J Clin Dermatol</addtitle><date>2024-11-01</date><risdate>2024</risdate><volume>25</volume><issue>6</issue><spage>951</spage><epage>966</epage><pages>951-966</pages><issn>1175-0561</issn><issn>1179-1888</issn><eissn>1179-1888</eissn><abstract>Cannabidiol (CBD) is a non-psychotropic cannabinoid with multiple pharmacological properties. Cannabidiol has attracted growing attention in the cosmetic industry, with an increasing number of CBD-containing skincare products on the market in recent years. The aim of this review is to evaluate the current evidence on the use of CBD for cosmetic purposes. Following an overview of CBD and the endocannabinoid system in the skin, we summarize pre-clinical and clinical studies that address the potential of CBD in cosmetic dermatology. Available in vitro and in vivo evidence suggests that CBD has anti-oxidant, anti-inflammatory, moisturizing, anti-acne, wound-healing, and anti-aging properties. However, only a few clinical studies have been conducted on the use of CBD in the skin. In addition, there is a critical need to develop an efficient drug-delivery system for topical/transdermal application of CBD. Further research, including clinical and pharmacokinetic studies, are needed to fully evaluate the role of CBD in cosmetic dermatology.</abstract><cop>Cham</cop><pub>Springer International Publishing</pub><pmid>39369127</pmid><doi>10.1007/s40257-024-00891-y</doi><tpages>16</tpages><orcidid>https://orcid.org/0000-0002-8194-9140</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1175-0561 |
| ispartof | American journal of clinical dermatology, 2024-11, Vol.25 (6), p.951-966 |
| issn | 1175-0561 1179-1888 1179-1888 |
| language | eng |
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| subjects | Administration, Cutaneous Animals Anti-Inflammatory Agents - administration & dosage Anti-Inflammatory Agents - pharmacology Antioxidants Antioxidants - administration & dosage Antioxidants - pharmacology Binding sites Cannabidiol Cannabidiol - administration & dosage Cannabidiol - pharmacology Cannabidiol - therapeutic use Cosmetics - administration & dosage Dermatitis Dermatologic Agents - administration & dosage Dermatologic Agents - pharmacology Dermatologic Agents - therapeutic use Dermatology Dermatology - methods Enzymes Fatty acids Fibroblasts Homeostasis Humans Inflammation Medicine Medicine & Public Health Oxidative stress Pharmacology/Toxicology Pharmacotherapy Proteins Review Review Article Skin Skin - drug effects Skin - metabolism Skin Aging - drug effects Tetrahydrocannabinol THC Transcription factors Tumor necrosis factor-TNF Wound Healing - drug effects |
| title | The Potential Role of Cannabidiol in Cosmetic Dermatology: A Literature Review |
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