Analysis of Molecular Imaging Biomarkers Derived from [ 18 F]FDG PET/CT in mCRPC: Whole-Body Total Lesion Glycolysis (TLG) Predicts Overall Survival in Patients Undergoing [ 225 Ac]Ac-PSMA-617-Augmented [ 177 Lu]Lu-PSMA-617 Radioligand Therapy

The augmentation of [ Lu]Lu-PSMA-617 radioligand therapy by alpha emitting [ Ac]Ac-PSMA-617, known as the tandem therapy concept, is a promising escalating treatment option in advanced mCRPC. In this study, we evaluated the value of [ F]FDG PET/CT-derived molecular imaging biomarkers for predicting...

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Veröffentlicht in:	Cancers 2024-10, Vol.16 (20), p.3532
Hauptverfasser:	Burgard, Caroline, Khreish, Fadi, Dahlmanns, Lukas, Blickle, Arne, Bastian, Moritz B, Speicher, Tilman, Maus, Stephan, Schaefer-Schuler, Andrea, Bartholomä, Mark, Petto, Sven, Ezziddin, Samer, Rosar, Florian
Format:	Artikel
Sprache:	eng
Schlagworte:	Androgens Antigens Biomarkers Cancer therapies Castration Computed tomography FDA approval Glycolysis Medical imaging Medical prognosis Metastases Patients Positron emission tomography Prostate cancer Statistical analysis Survival Tomography
Online-Zugang:	Volltext
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