Capsular vascularization: role of suprachoroidal triamcinolone and histopathology
Neovascularization of the lens is a rare entity linked to lens-induced inflammation due to many causes like trauma. We describe a case managed using suprachoroidal triamcinolone, an anti-VEGF injection, in conjunction with cataract surgery and IOL implantation. A male patient, 27, presented with a s...
Gespeichert in:
| Veröffentlicht in: | Romanian journal of ophthalmology 2024-07, Vol.68 (3), p.321-324 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 324 |
|---|---|
| container_issue | 3 |
| container_start_page | 321 |
| container_title | Romanian journal of ophthalmology |
| container_volume | 68 |
| creator | Oli, Avadhesh Dhami, Simran Nair, Lakshmi Mutreja, Deepti Rao, Bhavaraj Veerabhadhra |
| description | Neovascularization of the lens is a rare entity linked to lens-induced inflammation due to many causes like trauma. We describe a case managed using suprachoroidal triamcinolone, an anti-VEGF injection, in conjunction with cataract surgery and IOL implantation.
A male patient, 27, presented with a severe reduction in vision in his right eye (RE) accompanied by redness for one month. He also had a distant history of blunt trauma to the RE approximately eight years before. His vision in the RE was reduced to hand motion and 20/20 in the left eye. Examining the anterior segment in RE revealed lenticular neovascularization, irregular anterior capsular thickening, iris sphincter tear at the 12 o'clock position, and fine KPs, with iris pigment clumps on the anterior capsule.
To reduce vascularization and inflammation, the patient was treated with intravitreal Anti-VEGF and suprachoroidal triamcinolone by an innovative technique, along with cataract surgery, following which visual acuity improved to 20/20.
In this exceptional case report, suprachoroidal TA has been used for the first time to treat ocular inflammation and vascularization in traumatic cataract with capsular neovascularization and lens-induced uveitis. |
| doi_str_mv | 10.22336/rjo.2024.58 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11503217</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3121281641</sourcerecordid><originalsourceid>FETCH-LOGICAL-c1878-effa029648838f3c4c07b62952fc43d5aaa1213551677a05da85474b67b9b4493</originalsourceid><addsrcrecordid>eNpVkc1LxDAQxYMoKro3z9KjB7vms0m9iCx-gSCCnsM0TW0k29SkXVj_equroqcZZn68ecxD6IjgOaWMFWfxNcwppnwu1BbapwKTnArGtqeeC5lzRsUemqX0ijEmJS-xELtoj5W84FKyffS4gD6NHmK2gmQ-G_cOgwvdeRaDt1losjT2EUwbYnA1-GyIDpbGdcGHzmbQ1Vnr0hB6GNpp9LI-RDsN-GRn3_UAPV9fPS1u8_uHm7vF5X1uiJIqt00DmJYFV4qphhlusKwKWgraGM5qAQCEEiYEKaQELGpQgkteFbIqK85LdoAuNrr9WC1tbWw3RPC6j24Jca0DOP1_07lWv4SVJkRgRomcFE6-FWJ4G20a9NIlY72HzoYxaTYZoIoUnEzo6QY1MaQUbfN7h2D9lYSektCfSWihJvz4r7df-Ofv7AOh3oXY</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3121281641</pqid></control><display><type>article</type><title>Capsular vascularization: role of suprachoroidal triamcinolone and histopathology</title><source>MEDLINE</source><source>PubMed Central</source><creator>Oli, Avadhesh ; Dhami, Simran ; Nair, Lakshmi ; Mutreja, Deepti ; Rao, Bhavaraj Veerabhadhra</creator><creatorcontrib>Oli, Avadhesh ; Dhami, Simran ; Nair, Lakshmi ; Mutreja, Deepti ; Rao, Bhavaraj Veerabhadhra</creatorcontrib><description>Neovascularization of the lens is a rare entity linked to lens-induced inflammation due to many causes like trauma. We describe a case managed using suprachoroidal triamcinolone, an anti-VEGF injection, in conjunction with cataract surgery and IOL implantation.
A male patient, 27, presented with a severe reduction in vision in his right eye (RE) accompanied by redness for one month. He also had a distant history of blunt trauma to the RE approximately eight years before. His vision in the RE was reduced to hand motion and 20/20 in the left eye. Examining the anterior segment in RE revealed lenticular neovascularization, irregular anterior capsular thickening, iris sphincter tear at the 12 o'clock position, and fine KPs, with iris pigment clumps on the anterior capsule.
To reduce vascularization and inflammation, the patient was treated with intravitreal Anti-VEGF and suprachoroidal triamcinolone by an innovative technique, along with cataract surgery, following which visual acuity improved to 20/20.
In this exceptional case report, suprachoroidal TA has been used for the first time to treat ocular inflammation and vascularization in traumatic cataract with capsular neovascularization and lens-induced uveitis.</description><identifier>ISSN: 2457-4325</identifier><identifier>ISSN: 2501-2533</identifier><identifier>EISSN: 2501-2533</identifier><identifier>DOI: 10.22336/rjo.2024.58</identifier><identifier>PMID: 39464773</identifier><language>eng</language><publisher>Romania: Romanian Society of Ophthalmology</publisher><subject>Adult ; Case Report ; Choroid - blood supply ; Eye Injuries - complications ; Eye Injuries - diagnosis ; Glucocorticoids - therapeutic use ; Humans ; Intravitreal Injections ; Lens Capsule, Crystalline ; Lens Implantation, Intraocular - methods ; Male ; Neovascularization, Pathologic - drug therapy ; Triamcinolone Acetonide - administration & dosage ; Triamcinolone Acetonide - therapeutic use ; Visual Acuity</subject><ispartof>Romanian journal of ophthalmology, 2024-07, Vol.68 (3), p.321-324</ispartof><rights>2024 The Authors.</rights><rights>2024 The Authors 2024</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11503217/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11503217/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,725,778,782,883,27911,27912,53778,53780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39464773$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Oli, Avadhesh</creatorcontrib><creatorcontrib>Dhami, Simran</creatorcontrib><creatorcontrib>Nair, Lakshmi</creatorcontrib><creatorcontrib>Mutreja, Deepti</creatorcontrib><creatorcontrib>Rao, Bhavaraj Veerabhadhra</creatorcontrib><title>Capsular vascularization: role of suprachoroidal triamcinolone and histopathology</title><title>Romanian journal of ophthalmology</title><addtitle>Rom J Ophthalmol</addtitle><description>Neovascularization of the lens is a rare entity linked to lens-induced inflammation due to many causes like trauma. We describe a case managed using suprachoroidal triamcinolone, an anti-VEGF injection, in conjunction with cataract surgery and IOL implantation.
A male patient, 27, presented with a severe reduction in vision in his right eye (RE) accompanied by redness for one month. He also had a distant history of blunt trauma to the RE approximately eight years before. His vision in the RE was reduced to hand motion and 20/20 in the left eye. Examining the anterior segment in RE revealed lenticular neovascularization, irregular anterior capsular thickening, iris sphincter tear at the 12 o'clock position, and fine KPs, with iris pigment clumps on the anterior capsule.
To reduce vascularization and inflammation, the patient was treated with intravitreal Anti-VEGF and suprachoroidal triamcinolone by an innovative technique, along with cataract surgery, following which visual acuity improved to 20/20.
In this exceptional case report, suprachoroidal TA has been used for the first time to treat ocular inflammation and vascularization in traumatic cataract with capsular neovascularization and lens-induced uveitis.</description><subject>Adult</subject><subject>Case Report</subject><subject>Choroid - blood supply</subject><subject>Eye Injuries - complications</subject><subject>Eye Injuries - diagnosis</subject><subject>Glucocorticoids - therapeutic use</subject><subject>Humans</subject><subject>Intravitreal Injections</subject><subject>Lens Capsule, Crystalline</subject><subject>Lens Implantation, Intraocular - methods</subject><subject>Male</subject><subject>Neovascularization, Pathologic - drug therapy</subject><subject>Triamcinolone Acetonide - administration & dosage</subject><subject>Triamcinolone Acetonide - therapeutic use</subject><subject>Visual Acuity</subject><issn>2457-4325</issn><issn>2501-2533</issn><issn>2501-2533</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkc1LxDAQxYMoKro3z9KjB7vms0m9iCx-gSCCnsM0TW0k29SkXVj_equroqcZZn68ecxD6IjgOaWMFWfxNcwppnwu1BbapwKTnArGtqeeC5lzRsUemqX0ijEmJS-xELtoj5W84FKyffS4gD6NHmK2gmQ-G_cOgwvdeRaDt1losjT2EUwbYnA1-GyIDpbGdcGHzmbQ1Vnr0hB6GNpp9LI-RDsN-GRn3_UAPV9fPS1u8_uHm7vF5X1uiJIqt00DmJYFV4qphhlusKwKWgraGM5qAQCEEiYEKaQELGpQgkteFbIqK85LdoAuNrr9WC1tbWw3RPC6j24Jca0DOP1_07lWv4SVJkRgRomcFE6-FWJ4G20a9NIlY72HzoYxaTYZoIoUnEzo6QY1MaQUbfN7h2D9lYSektCfSWihJvz4r7df-Ofv7AOh3oXY</recordid><startdate>202407</startdate><enddate>202407</enddate><creator>Oli, Avadhesh</creator><creator>Dhami, Simran</creator><creator>Nair, Lakshmi</creator><creator>Mutreja, Deepti</creator><creator>Rao, Bhavaraj Veerabhadhra</creator><general>Romanian Society of Ophthalmology</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>202407</creationdate><title>Capsular vascularization: role of suprachoroidal triamcinolone and histopathology</title><author>Oli, Avadhesh ; Dhami, Simran ; Nair, Lakshmi ; Mutreja, Deepti ; Rao, Bhavaraj Veerabhadhra</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1878-effa029648838f3c4c07b62952fc43d5aaa1213551677a05da85474b67b9b4493</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Adult</topic><topic>Case Report</topic><topic>Choroid - blood supply</topic><topic>Eye Injuries - complications</topic><topic>Eye Injuries - diagnosis</topic><topic>Glucocorticoids - therapeutic use</topic><topic>Humans</topic><topic>Intravitreal Injections</topic><topic>Lens Capsule, Crystalline</topic><topic>Lens Implantation, Intraocular - methods</topic><topic>Male</topic><topic>Neovascularization, Pathologic - drug therapy</topic><topic>Triamcinolone Acetonide - administration & dosage</topic><topic>Triamcinolone Acetonide - therapeutic use</topic><topic>Visual Acuity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Oli, Avadhesh</creatorcontrib><creatorcontrib>Dhami, Simran</creatorcontrib><creatorcontrib>Nair, Lakshmi</creatorcontrib><creatorcontrib>Mutreja, Deepti</creatorcontrib><creatorcontrib>Rao, Bhavaraj Veerabhadhra</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Romanian journal of ophthalmology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Oli, Avadhesh</au><au>Dhami, Simran</au><au>Nair, Lakshmi</au><au>Mutreja, Deepti</au><au>Rao, Bhavaraj Veerabhadhra</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Capsular vascularization: role of suprachoroidal triamcinolone and histopathology</atitle><jtitle>Romanian journal of ophthalmology</jtitle><addtitle>Rom J Ophthalmol</addtitle><date>2024-07</date><risdate>2024</risdate><volume>68</volume><issue>3</issue><spage>321</spage><epage>324</epage><pages>321-324</pages><issn>2457-4325</issn><issn>2501-2533</issn><eissn>2501-2533</eissn><abstract>Neovascularization of the lens is a rare entity linked to lens-induced inflammation due to many causes like trauma. We describe a case managed using suprachoroidal triamcinolone, an anti-VEGF injection, in conjunction with cataract surgery and IOL implantation.
A male patient, 27, presented with a severe reduction in vision in his right eye (RE) accompanied by redness for one month. He also had a distant history of blunt trauma to the RE approximately eight years before. His vision in the RE was reduced to hand motion and 20/20 in the left eye. Examining the anterior segment in RE revealed lenticular neovascularization, irregular anterior capsular thickening, iris sphincter tear at the 12 o'clock position, and fine KPs, with iris pigment clumps on the anterior capsule.
To reduce vascularization and inflammation, the patient was treated with intravitreal Anti-VEGF and suprachoroidal triamcinolone by an innovative technique, along with cataract surgery, following which visual acuity improved to 20/20.
In this exceptional case report, suprachoroidal TA has been used for the first time to treat ocular inflammation and vascularization in traumatic cataract with capsular neovascularization and lens-induced uveitis.</abstract><cop>Romania</cop><pub>Romanian Society of Ophthalmology</pub><pmid>39464773</pmid><doi>10.22336/rjo.2024.58</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2457-4325 |
| ispartof | Romanian journal of ophthalmology, 2024-07, Vol.68 (3), p.321-324 |
| issn | 2457-4325 2501-2533 2501-2533 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11503217 |
| source | MEDLINE; PubMed Central |
| subjects | Adult Case Report Choroid - blood supply Eye Injuries - complications Eye Injuries - diagnosis Glucocorticoids - therapeutic use Humans Intravitreal Injections Lens Capsule, Crystalline Lens Implantation, Intraocular - methods Male Neovascularization, Pathologic - drug therapy Triamcinolone Acetonide - administration & dosage Triamcinolone Acetonide - therapeutic use Visual Acuity |
| title | Capsular vascularization: role of suprachoroidal triamcinolone and histopathology |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-15T19%3A01%3A56IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Capsular%20vascularization:%20role%20of%20suprachoroidal%20triamcinolone%20and%20histopathology&rft.jtitle=Romanian%20journal%20of%20ophthalmology&rft.au=Oli,%20Avadhesh&rft.date=2024-07&rft.volume=68&rft.issue=3&rft.spage=321&rft.epage=324&rft.pages=321-324&rft.issn=2457-4325&rft.eissn=2501-2533&rft_id=info:doi/10.22336/rjo.2024.58&rft_dat=%3Cproquest_pubme%3E3121281641%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=3121281641&rft_id=info:pmid/39464773&rfr_iscdi=true |